# Vitamin K epoxide reductase complex subunit 1

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21175110](https://www.wikidata.org/wiki/Q21175110)  
**Source**: https://4ort.xyz/entity/vitamin-k-epoxide-reductase-complex-subunit-1-q21175110


## References

1. UniProt
2. IUPHAR/BPS Guide to PHARMACOLOGY
3. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL711)
4. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q9BQB6)
5. Q20641742
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BQB6)
7. [Site-directed mutagenesis of coumarin-type anticoagulant-sensitive VKORC1: evidence that highly conserved amino acids define structural requirements for enzymatic activity and inhibition by warfarin](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BQB6&geneProductId=UniProtKB:Q9BQB6)
8. [The vitamin K oxidoreductase is a multimer that efficiently reduces vitamin K epoxide to hydroquinone to allow vitamin K-dependent protein carboxylation](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BQB6&geneProductId=UniProtKB:Q9BQB6)
9. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BQB6&geneProductId=UniProtKB:Q9BQB6)
10. [Site-directed mutagenesis of coumarin-type anticoagulant-sensitive VKORC1: evidence that highly conserved amino acids define structural requirements for enzymatic activity and inhibition by warfarin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BQB6)
11. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BQB6)
12. [Novel insight into the mechanism of the vitamin K oxidoreductase (VKOR): electron relay through Cys43 and Cys51 reduces VKOR to allow vitamin K reduction and facilitation of vitamin K-dependent protein carboxylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BQB6)
13. Ensembl Release 99