# Vinculin

> mammalian protein found in Homo sapiens

**Wikidata**: [Q424042](https://www.wikidata.org/wiki/Q424042)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/Vinculin)  
**Source**: https://4ort.xyz/entity/vinculin


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P18206)
3. Q20641742
4. Freebase Data Dumps. 2013
5. [Vinculin regulates cell-surface E-cadherin expression by binding to beta-catenin](http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206)
6. [beta-Dystroglycan modulates the interplay between actin and microtubules in human-adhered platelets](http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206)
7. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206)
8. [Vinexin: a novel vinculin-binding protein with multiple SH3 domains enhances actin cytoskeletal organization](http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206)
9. [Human alpha-synemin interacts directly with vinculin and metavinculin](http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206)
10. [Integrin-mediated cell adhesion: the cytoskeletal connection](http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206)
11. [RNA and RNA binding proteins participate in early stages of cell spreading through spreading initiation centers](http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206)
12. [Structural dynamics of alpha-actinin-vinculin interactions](http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206)
13. [Structural basis for amplifying vinculin activation by talin](http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206)
14. [KIAA1797/FOCAD encodes a novel focal adhesion protein with tumour suppressor function in gliomas](http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206)
15. [Monocyte cells and cancer cells express novel paxillin isoforms with different binding properties to focal adhesion proteins](http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206)
16. [Dimer asymmetry defines α-catenin interactions](http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206)
17. [Raver1 Interactions with Vinculin and RNA Suggest a Feed-Forward Pathway in Directing mRNA to Focal Adhesions](http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206)
18. [Recruitment of the Arp2/3 complex to vinculin: coupling membrane protrusion to matrix adhesion](http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206)
19. [Capping of actin filaments by vinculin activated by the Shigella IpaA carboxyl-terminal domain](http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206)
20. [Vinculin binding in its closed conformation by a helix addition mechanism](http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206)
21. [Structural mimicry for vinculin activation by IpaA, a virulence factor of Shigella flexneri](http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206)
22. [A proteome-scale map of the human interactome network](http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206)
23. [CAP interacts with cytoskeletal proteins and regulates adhesion-mediated ERK activation and motility](http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206)
24. [Role of dystrophins and utrophins in platelet adhesion process](http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206)
25. [F-actin binding site masked by the intramolecular association of vinculin head and tail domains](http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206)
26. [alpha-Catenin-vinculin interaction functions to organize the apical junctional complex in epithelial cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206)
27. [Proteomic analysis of increased Parkin expression and its interactants provides evidence for a role in modulation of mitochondrial function](http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206)
28. [E-cadherin interactome complexity and robustness resolved by quantitative proteomics](http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206)
29. [Proteomic analysis of cerebrospinal fluid extracellular vesicles: a comprehensive dataset](http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206)
30. [Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206)
31. [Complete sequence of human vinculin and assignment of the gene to chromosome 10](http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206)
32. [Flotillin-1 facilitates toll-like receptor 3 signaling in human endothelial cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206)
33. [Spatial and temporal expression of the β1D integrin during mouse development](http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206)
34. [Proteomics of human umbilical vein endothelial cells applied to etoposide-induced apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206)
35. [MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206)
36. [Large-scale proteomics and phosphoproteomics of urinary exosomes](http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206)
37. [Vinculin--a dynamic regulator of cell adhesion](http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206)
38. [Cytoskeletal proteins talin and vinculin in integrin-mediated adhesion](http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206)
39. [Platelet Proteome Analysis Reveals Integrin-dependent Aggregation Defects in Patients with Myelodysplastic Syndromes](http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206)
40. Ensembl Release 99
41. Identifiers.org
42. [OpenAlex](https://docs.openalex.org/download-snapshot/snapshot-data-format)