# Vav guanine nucleotide exchange factor 2

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21111124](https://www.wikidata.org/wiki/Q21111124)  
**Source**: https://4ort.xyz/entity/vav-guanine-nucleotide-exchange-factor-2


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P52735)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52735)
5. [Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52735)
6. [Structural basis for a novel interaction between TXNIP and Vav2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52735)
7. [A quantitative protein interaction network for the ErbB receptors using protein microarrays](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52735)
8. [Regulation of NK cell-mediated cytotoxicity by the adaptor protein 3BP2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52735)
9. [The adaptor protein 3BP2 associates with VAV guanine nucleotide exchange factors to regulate NFAT activation by the B-cell antigen receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52735)
10. [Identification of multi-SH3 domain-containing protein interactome in pancreatic cancer: a yeast two-hybrid approach](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52735)
11. [Novel association of Vav2 and Nek3 modulates signaling through the human prolactin receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52735)
12. [Enhanced prediction of Src homology 2 (SH2) domain binding potentials using a fluorescence polarization-derived c-Met, c-Kit, ErbB, and androgen receptor interactome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52735)
13. [Tyrosine-phosphorylated caveolin-1 blocks bacterial uptake by inducing Vav2-RhoA-mediated cytoskeletal rearrangements](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52735)
14. [Abi1/Hssh3bp1 pY213 links Abl kinase signaling to p85 regulatory subunit of PI-3 kinase in regulation of macropinocytosis in LNCaP cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52735)
15. [Tarp regulates early Chlamydia-induced host cell survival through interactions with the human adaptor protein SHC1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52735)
16. [Radixin regulates cell migration and cell-cell adhesion through Rac1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52735)
17. [Identification of VAV2 on 9q34 and its exclusion as the tuberous sclerosis gene TSC1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52735)
18. Ensembl Release 99