# Valosin containing protein

> mammalian protein found in Mus musculus

**Wikidata**: [Q21499477](https://www.wikidata.org/wiki/Q21499477)  
**Source**: https://4ort.xyz/entity/valosin-containing-protein-q21499477


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q01853)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01853)
5. [Function of the p97-Ufd1-Npl4 complex in retrotranslocation from the ER to the cytosol: dual recognition of nonubiquitinated polypeptide segments and polyubiquitin chains](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01853)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01853&geneProductId=UniProtKB:Q01853)
7. [Valosin-containing protein is a multi-ubiquitin chain-targeting factor required in ubiquitin-proteasome degradation](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01853&geneProductId=UniProtKB:Q01853)
8. [Function of the p97-Ufd1-Npl4 complex in retrotranslocation from the ER to the cytosol: dual recognition of nonubiquitinated polypeptide segments and polyubiquitin chains](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01853&geneProductId=UniProtKB:Q01853)
9. [Characterization of the mouse gene for the U-box-type ubiquitin ligase UFD2a](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01853)
10. [USP13 antagonizes gp78 to maintain functionality of a chaperone in ER-associated degradation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01853)
11. [A complex of mammalian ufd1 and npl4 links the AAA-ATPase, p97, to ubiquitin and nuclear transport pathways](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01853)
12. [Polycystin-2 is regulated by endoplasmic reticulum-associated degradation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01853)
13. [Molecular Components of a Cell Death Pathway Activated by Endoplasmic Reticulum Stress](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01853)
14. [ER-stress-inducible Herp, facilitates the degradation of immature nicastrin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01853)
15. [RAB-like 2 has an essential role in male fertility, sperm intra-flagellar transport, and tail assembly](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01853)
16. [An arginine/lysine-rich motif is crucial for VCP/p97-mediated modulation of ataxin-3 fibrillogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01853)
17. [Glycoprotein-specific ubiquitin ligases recognize N-glycans in unfolded substrates](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01853)
18. [Structural basis of the interaction between the AAA ATPase p97/VCP and its adaptor protein p47](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01853)
19. [An Armadillo motif in Ufd3 interacts with Cdc48 and is involved in ubiquitin homeostasis and protein degradation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01853)
20. [Identification of components of the murine histone deacetylase 6 complex: link between acetylation and ubiquitination signaling pathways](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01853)
21. [Signal-peptide-mediated translocation is regulated by a p97-AIRAPL complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01853)
22. [The p97/VCP ATPase is critical in muscle atrophy and the accelerated degradation of muscle proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01853)
23. [The AAA ATPase p97 links peptide N-glycanase to the endoplasmic reticulum-associated E3 ligase autocrine motility factor receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01853)
24. [Studies on peptide:N-glycanase-p97 interaction suggest that p97 phosphorylation modulates endoplasmic reticulum-associated degradation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01853)
25. [A stress-responsive system for mitochondrial protein degradation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01853)
26. [Distinct conformations of the protein complex p97-Ufd1-Npl4 revealed by electron cryomicroscopy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01853)
27. [Isolation of a point-mutated p47 lacking binding affinity to p97ATPase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01853)
28. [A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01853)
29. [Structural insights into the p97-Ufd1-Npl4 complex.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01853)
30. [Regulation of retrotranslocation by p97-associated deubiquitinating enzyme ataxin-3](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01853)
31. [Improved structures of full-length p97, an AAA ATPase: implications for mechanisms of nucleotide-dependent conformational change](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01853)
32. [Nucleotide dependent motion and mechanism of action of p97/VCP](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01853)
33. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01853)
34. [Valosin-containing protein is a multi-ubiquitin chain-targeting factor required in ubiquitin-proteasome degradation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01853)
35. [SDF2L1 interacts with the ER-associated degradation machinery and retards the degradation of mutant proinsulin in pancreatic β-cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01853&geneProductId=UniProtKB:Q01853)
36. [Proteolipid protein is required for transport of sirtuin 2 into CNS myelin](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01853&geneProductId=UniProtKB:Q01853)
37. [HDAC6 controls major cell response pathways to cytotoxic accumulation of protein aggregates](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01853)
38. [A complex of mammalian ufd1 and npl4 links the AAA-ATPase, p97, to ubiquitin and nuclear transport pathways](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01853&geneProductId=UniProtKB:Q01853)
39. [Regulation of retrotranslocation by p97-associated deubiquitinating enzyme ataxin-3](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01853&geneProductId=UniProtKB:Q01853)
40. [SDF2L1 interacts with the ER-associated degradation machinery and retards the degradation of mutant proinsulin in pancreatic β-cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01853)
41. [Proteolipid protein is required for transport of sirtuin 2 into CNS myelin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01853)
42. [Molecular characterization and comparison of the components and multiprotein complexes in the postsynaptic proteome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01853)
43. [The proteome of the presynaptic active zone from mouse brain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01853)
44. [HDAC6-p97/VCP controlled polyubiquitin chain turnover](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01853)
45. [Pathogenic VCP mutations induce mitochondrial uncoupling and reduced ATP levels](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01853)
46. [Loss of the proteostasis factor AIRAPL causes myeloid transformation by deregulating IGF-1 signaling.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01853)
47. ensembl Release 106