# Urocortin

> mammalian protein found in Rattus norvegicus

**Wikidata**: [Q28557273](https://www.wikidata.org/wiki/Q28557273)  
**Source**: https://4ort.xyz/entity/urocortin-q28557273


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P55090)
3. Q20641742
4. [Urocortin, But Not Urocortin II, Protects Cultured Hippocampal Neurons from Oxidative and Excitotoxic Cell Death via Corticotropin-Releasing Hormone Receptor Type I](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55090)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55090)
6. [Urocortin, a mammalian neuropeptide related to fish urotensin I and to corticotropin-releasing factor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55090)
7. [Genetically encoded chemical probes in cells reveal the binding path of urocortin-I to CRF class B GPCR](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55090)
8. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55090)
9. [Urocortin modulates dopaminergic neuronal survival via inhibition of glycogen synthase kinase-3β and histone deacetylase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55090)
10. [Ligand affinity for amino-terminal and juxtamembrane domains of the corticotropin releasing factor type I receptor: regulation by G-protein and nonpeptide antagonists](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55090)
11. [The localisation of urocortin in the adult rat cerebellum: a light and electron microscopic study](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55090)
12. [Distribution of corticotropin-releasing factor binding protein-immunoreactivity in the rat hypothalamus: association with corticotropin-releasing factor-, urocortin 1- and vimentin-immunoreactive fibres](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55090)
13. [Urocortin expression in rat brain: evidence against a pervasive relationship of urocortin-containing projections with targets bearing type 2 CRF receptors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55090)
14. [Protective effects of the urocortin homologues stresscopin (SCP) and stresscopin-related peptide (SRP) against hypoxia/reoxygenation injury in rat neonatal cardiomyocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55090)
15. [Enhanced expression of urocortin in lung tissues of rats with allergic asthma](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55090)
16. [Reduced urocortin 1 immunoreactivity in the non-preganglionic Edinger-Westphal nucleus during late pregnancy in rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55090)
17. [Urocortin shares the memory modulating effects of corticotropin-releasing factor (CRF): mediation by CRF1 receptors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55090)
18. [Urocortin in the ventromedial hypothalamic nucleus acts as an inhibitor of feeding behavior in rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55090)
19. [Modulation of learning and anxiety by corticotropin-releasing factor (CRF) and stress: differential roles of CRF receptors 1 and 2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55090)
20. [Hypothalamic paraventricular nucleus injections of urocortin alter food intake and respiratory quotient](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55090)
21. [Urocortin 1 reduces food intake and ghrelin secretion via CRF2 receptors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55090)
22. [Urocortin protects cardiac myocytes from ischemia/reperfusion injury by attenuating calcium-insensitive phospholipase A2 gene expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55090)
23. [Stimulation of rat pancreatic exocrine secretion by urocortin and corticotropin releasing factor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55090)
24. [Hypertrophic effects of urocortin homologous peptides are mediated via activation of the Akt pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55090)
25. [Corticotropin-releasing factor and urocortin differentially modulate rat Purkinje cell dendritic outgrowth and differentiation in vitro](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55090)
26. [Estrogen receptors alpha and beta differentially regulate the transcriptional activity of the Urocortin gene](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55090)
27. [Urocortin-Related Peptides Increase Interleukin-6 Output via Cyclic Adenosine 5′-Monophosphate-Dependent Pathways in A7r5 Aortic Smooth Muscle Cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55090)
28. [Urocortin, a member of the corticotropin-releasing factor family, in normal and diseased heart](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55090)
29. [Urocortin induces positive inotropic effect in rat heart](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55090)
30. [Injections of urocortin 1 into the basolateral amygdala induce anxiety-like behavior and c-Fos expression in brainstem serotonergic neurons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55090)
31. [Local secretion of urocortin 1 promotes microvascular permeability during lipopolysaccharide-induced inflammation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55090)
32. [Analysis of the mechanism of the vasodepressor effect of urocortin in anesthetized rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55090)
33. [Differential responses of corticotropin-releasing factor and urocortin 1 to acute pain stress in the rat brain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55090)
34. [Corticotropin-releasing factor and Urocortin I modulate excitatory glutamatergic synaptic transmission](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55090)
35. [Cardioprotective activity of urocortin by preventing caspase-independent, non-apoptotic death in cultured neonatal rat cardiomyocytes exposed to ischemia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55090)
36. [Modulation of Ca2+ influx by corticotropin-releasing factor (CRF) family of peptides via CRF receptors in rat pancreatic beta-cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55090)
37. ensembl Release 106