# Unpaired 1 Dmel_CG5993

> protein found in Drosophila melanogaster

**Wikidata**: [Q29820452](https://www.wikidata.org/wiki/Q29820452)  
**Source**: https://4ort.xyz/entity/unpaired-1-dmel-cg5993


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q9VWW4)
3. Q20641742
4. [The roles of JAK/STAT signaling in Drosophila immune responses](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VWW4&geneProductId=UniProtKB:Q9VWW4)
5. [The Fertile Field of Drosophila JAK/STAT Signalling](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VWW4&geneProductId=UniProtKB:Q9VWW4)
6. [The JAK/STAT pathway and Drosophila development](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VWW4&geneProductId=UniProtKB:Q9VWW4)
7. [Characterisation of Upd2, a Drosophila JAK/STAT pathway ligand](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VWW4&geneProductId=UniProtKB:Q9VWW4)
8. [Differential activities of the Drosophila JAK/STAT pathway ligands Upd, Upd2 and Upd3](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VWW4&geneProductId=UniProtKB:Q9VWW4)
9. [The polarisation of the anteroposterior axis in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VWW4&geneProductId=UniProtKB:Q9VWW4)
10. [The JAK/STAT Signaling Pathway Is Required for the Initial Choice of Sexual Identity in Drosophila melanogaster](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VWW4&geneProductId=UniProtKB:Q9VWW4)
11. [Asymmetric localisation of cytokine mRNA is essential for JAK/STAT activation during cell invasiveness](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VWW4&geneProductId=UniProtKB:Q9VWW4)
12. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VWW4&geneProductId=UniProtKB:Q9VWW4)
13. [Drosophila unpaired encodes a secreted protein that activates the JAK signaling pathway](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VWW4&geneProductId=UniProtKB:Q9VWW4)
14. [Long‐range effect of upd, a ligand for Jak/STAT pathway, on cell cycle in Drosophila eye development](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VWW4&geneProductId=UniProtKB:Q9VWW4)
15. [Repression of Wasp by JAK/STAT signalling inhibits medial actomyosin network assembly and apical cell constriction in intercalating epithelial cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VWW4&geneProductId=UniProtKB:Q9VWW4)
16. [A Gradient of JAK Pathway Activity Patterns the Anterior-Posterior Axis of the Follicular Epithelium](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VWW4&geneProductId=UniProtKB:Q9VWW4)
17. [Cooperation of JAK/STAT and Notch signaling in the Drosophila foregut](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VWW4&geneProductId=UniProtKB:Q9VWW4)
18. [Localized JAK/STAT signaling is required for oriented cell rearrangement in a tubular epithelium](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VWW4&geneProductId=UniProtKB:Q9VWW4)
19. [JAK/STAT signaling promotes regional specification by negatively regulatingwinglessexpression inDrosophila](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VWW4&geneProductId=UniProtKB:Q9VWW4)
20. [Structure, function and evolution of sex-determining systems in Dipteran insects](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VWW4&geneProductId=UniProtKB:Q9VWW4)
21. [Cytokine signaling through the JAK/STAT pathway is required for long-term memory in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VWW4&geneProductId=UniProtKB:Q9VWW4)
22. [A Screen of Cell-Surface Molecules Identifies Leucine-Rich Repeat Proteins as Key Mediators of Synaptic Target Selection](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VWW4&geneProductId=UniProtKB:Q9VWW4)
23. [Control of Stem Cell Self-Renewal in Drosophila Spermatogenesis by JAK-STAT Signaling](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VWW4&geneProductId=UniProtKB:Q9VWW4)
24. [Stem Cell Self-Renewal Specified by JAK-STAT Activation in Response to a Support Cell Cue](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VWW4&geneProductId=UniProtKB:Q9VWW4)
25. [Dynamics of the basement membrane in invasive epithelial clusters inDrosophila](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VWW4&geneProductId=UniProtKB:Q9VWW4)
26. [Nucleoporin98-96 Function Is Required for Transit Amplification Divisions in the Germ Line of Drosophila melanogaster](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VWW4&geneProductId=UniProtKB:Q9VWW4)
27. [Autocrine and paracrine unpaired signaling regulate intestinal stem cell maintenance and division](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VWW4&geneProductId=UniProtKB:Q9VWW4)
28. [The stem-cell niche theory: lessons from flies](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VWW4&geneProductId=UniProtKB:Q9VWW4)
29. [Dissecting the mechanisms of Notch induced hyperplasia](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VWW4&geneProductId=UniProtKB:Q9VWW4)
30. [Regulation of Circadian Behavioral Output via a MicroRNA-JAK/STAT Circuit](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VWW4&geneProductId=UniProtKB:Q9VWW4)
31. [Genome-Wide RNAi Screen Identifies Genes Involved in Intestinal Pathogenic Bacterial Infection](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VWW4&geneProductId=UniProtKB:Q9VWW4)
32. [The endocytic control of JAK/STAT signalling in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VWW4&geneProductId=UniProtKB:Q9VWW4)
33. ensembl Release 106