# Uncoupling protein 2

> mammalian protein found in Rattus norvegicus

**Wikidata**: [Q28560571](https://www.wikidata.org/wiki/Q28560571)  
**Source**: https://4ort.xyz/entity/uncoupling-protein-2


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P56500)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56500)
5. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56500)
6. [Proliferation and differentiation of osteoblasts from the mandible of osteoporotic rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56500)
7. [Superoxide activates mitochondrial uncoupling protein 2 from the matrix side. Studies using targeted antioxidants](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56500)
8. [Genomic modulation of mitochondrial respiratory genes in the hypertrophied heart reflects adaptive changes in mitochondrial and contractile function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56500)
9. [Antioxidant defenses in the rat placenta in late gestation: increased labyrinthine expression of superoxide dismutases, glutathione peroxidase 3, and uncoupling protein 2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56500)
10. [Testicular aging involves mitochondrial dysfunction as well as an increase in UCP2 levels and proton leak](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56500)
11. [Nutritional and hormonal regulation of uncoupling protein gene expression in rat adipocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56500)
12. [Cyanide-induced death of dopaminergic cells is mediated by uncoupling protein-2 up-regulation and reduced Bcl-2 expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56500)
13. [Dynamic regulation of uncoupling protein 2 content in INS-1E insulinoma cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56500)
14. [UCP2 protects hypothalamic cells from TNF-alpha-induced damage](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56500)
15. [Uncoupling protein-2 attenuates glucose-stimulated insulin secretion in INS-1E insulinoma cells by lowering mitochondrial reactive oxygen species](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56500)
16. [Protection of regenerating liver after partial hepatectomy from carbon tetrachloride hepatotoxicity in rats: roles of mitochondrial uncoupling protein 2 and ATP stores](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56500)
17. [Loss of UCP2 impairs cold-induced non-shivering thermogenesis by promoting a shift toward glucose utilization in brown adipose tissue.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56500)
18. ensembl Release 106