# Ubiquitin specific peptidase 8

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21105620](https://www.wikidata.org/wiki/Q21105620)  
**Source**: https://4ort.xyz/entity/ubiquitin-specific-peptidase-8


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P40818)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40818)
5. [Final stages of cytokinesis and midbody ring formation are controlled by BRUCE](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40818)
6. [The MIT domain of UBPY constitutes a CHMP binding and endosomal localization signal required for efficient epidermal growth factor receptor degradation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40818)
7. [Ab initio protein modelling reveals novel human MIT domains](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40818)
8. [Interactions with LC3 and polyubiquitin chains link nbr1 to autophagic protein turnover](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40818)
9. [HIF1α deubiquitination by USP8 is essential for ciliogenesis in normoxia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40818)
10. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P40818&geneProductId=UniProtKB:P40818)
11. [UBPY: a growth-regulated human ubiquitin isopeptidase.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P40818&geneProductId=UniProtKB:P40818)
12. [The ubiquitin isopeptidase UBPY regulates endosomal ubiquitin dynamics and is essential for receptor down-regulation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P40818&geneProductId=UniProtKB:P40818)
13. [Dynamic regulation of ubiquitylation and deubiquitylation at the central spindle during cytokinesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P40818&geneProductId=UniProtKB:P40818)
14. [Deubiquitinating enzymes: a new class of biological regulators](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40818)
15. [E-cadherin interactome complexity and robustness resolved by quantitative proteomics](http://www.ebi.ac.uk/QuickGO/annotations?protein=P40818&geneProductId=UniProtKB:P40818)
16. [UBPY: a growth-regulated human ubiquitin isopeptidase.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40818)
17. [The ubiquitin isopeptidase UBPY regulates endosomal ubiquitin dynamics and is essential for receptor down-regulation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40818)
18. [Dynamic regulation of ubiquitylation and deubiquitylation at the central spindle during cytokinesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40818)
19. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40818)
20. [E-cadherin interactome complexity and robustness resolved by quantitative proteomics](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40818)
21. [Balanced ubiquitylation and deubiquitylation of Frizzled regulate cellular responsiveness to Wg/Wnt](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40818)
22. [The Endosome-associated Deubiquitinating Enzyme USP8 Regulates BACE1 Enzyme Ubiquitination and Degradation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P40818&geneProductId=UniProtKB:P40818)
23. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=P40818&geneProductId=UniProtKB:P40818)
24. [The Endosome-associated Deubiquitinating Enzyme USP8 Regulates BACE1 Enzyme Ubiquitination and Degradation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40818)
25. Ensembl Release 99