# Ubiquitin specific peptidase 22

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21112578](https://www.wikidata.org/wiki/Q21112578)  
**Source**: https://4ort.xyz/entity/ubiquitin-specific-peptidase-22


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q9UPT9)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UPT9)
5. [A TFTC/STAGA Module Mediates Histone H2A and H2B Deubiquitination, Coactivates Nuclear Receptors, and Counteracts Heterochromatin Silencing](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UPT9)
6. [The Putative Cancer Stem Cell Marker USP22 Is a Subunit of the Human SAGA Complex Required for Activated Transcription and Cell-Cycle Progression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UPT9)
7. [Cytoplasmic ATXN7L3B Interferes with Nuclear Functions of the SAGA Deubiquitinase Module](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UPT9)
8. [A proteome-scale map of the human interactome network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UPT9)
9. [Defining the human deubiquitinating enzyme interaction landscape](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UPT9)
10. [USP22 is a positive regulator of NFATc2 on promoting IL2 expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UPT9)
11. [USP22 regulates cell proliferation by deubiquitinating the transcriptional regulator FBP1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UPT9)
12. [The expression patterns of deubiquitinating enzymes, USP22 and Usp22](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UPT9)
13. [A high-confidence interaction map identifies SIRT1 as a mediator of acetylation of USP22 and the SAGA coactivator complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UPT9)
14. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UPT9&geneProductId=UniProtKB:Q9UPT9)
15. [Human ATAC Is a GCN5/PCAF-containing acetylase complex with a novel NC2-like histone fold module that interacts with the TATA-binding protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UPT9)
16. [USP22, an hSAGA subunit and potential cancer stem cell marker, reverses the polycomb-catalyzed ubiquitylation of histone H2A](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UPT9)
17. Ensembl Release 99
18. [Identifiers.org](https://registry.identifiers.org/registry/uniprot)