# Ubiquitin conjugating enzyme E2 E1

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21131180](https://www.wikidata.org/wiki/Q21131180)  
**Source**: https://4ort.xyz/entity/ubiquitin-conjugating-enzyme-e2-e1


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P51965)
3. [Swiss-Prot](http://www.uniprot.org/uniprot/P51965.txt?version=161)
4. Q20641742
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51965)
6. [Link between the ubiquitin conjugation system and the ISG15 conjugation system: ISG15 conjugation to the UbcH6 ubiquitin E2 enzyme](http://www.ebi.ac.uk/QuickGO/annotations?protein=P51965&geneProductId=UniProtKB:P51965)
7. [Cloning of human ubiquitin-conjugating enzymes UbcH6 and UbcH7 (E2-F1) and characterization of their interaction with E6-AP and RSP5](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51965)
8. [MEX is a testis-specific E3 ubiquitin ligase that promotes death receptor-induced apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51965)
9. [Monoubiquitination of human histone H2B: the factors involved and their roles in HOX gene regulation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51965)
10. [The E2 ubiquitin-conjugating enzymes direct polyubiquitination to preferred lysines](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51965)
11. [E2~Ub conjugates regulate the kinase activity of Shigella effector OspG during pathogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51965)
12. [FIH Regulates Cellular Metabolism through Hydroxylation of the Deubiquitinase OTUB1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51965)
13. [A comprehensive framework of E2-RING E3 interactions of the human ubiquitin-proteasome system](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51965)
14. [Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51965)
15. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P51965&geneProductId=UniProtKB:P51965)
16. [The E2 ubiquitin-conjugating enzymes direct polyubiquitination to preferred lysines](http://www.ebi.ac.uk/QuickGO/annotations?protein=P51965&geneProductId=UniProtKB:P51965)
17. [Topors functions as an E3 ubiquitin ligase with specific E2 enzymes and ubiquitinates p53](http://www.ebi.ac.uk/QuickGO/annotations?protein=P51965&geneProductId=UniProtKB:P51965)
18. [Link between the ubiquitin conjugation system and the ISG15 conjugation system: ISG15 conjugation to the UbcH6 ubiquitin E2 enzyme](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51965)
19. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51965)
20. [Topors functions as an E3 ubiquitin ligase with specific E2 enzymes and ubiquitinates p53](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51965)
21. [The autoantigen Ro52 is an E3 ligase resident in the cytoplasm but enters the nucleus upon cellular exposure to nitric oxide](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51965)
22. [Monoubiquitination of human histone H2B: the factors involved and their roles in HOX gene regulation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P51965&geneProductId=UniProtKB:P51965)
23. [Human ubiquitin-protein ligase Nedd4: expression, subcellular localization and selective interaction with ubiquitin-conjugating enzymes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51965)
24. Ensembl Release 99