# Ubiquitin conjugating enzyme E2 D3

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21112096](https://www.wikidata.org/wiki/Q21112096)  
**Source**: https://4ort.xyz/entity/ubiquitin-conjugating-enzyme-e2-d3


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P61077)
3. [Swiss-Prot](http://www.uniprot.org/uniprot/P61077.txt?version=131)
4. Q20641742
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077)
6. [The UbL protein UBTD1 stably interacts with the UBE2D family of E2 ubiquitin conjugating enzymes](http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077)
7. [Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network](http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077)
8. [A comprehensive framework of E2-RING E3 interactions of the human ubiquitin-proteasome system](http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077)
9. [E2~Ub conjugates regulate the kinase activity of Shigella effector OspG during pathogenesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077)
10. [Physical and functional interactions between ZIP kinase and UbcH5](http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077)
11. [Towards a proteome-scale map of the human protein–protein interaction network](http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077)
12. [Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region](http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077)
13. [A cancer-associated RING finger protein, RNF43, is a ubiquitin ligase that interacts with a nuclear protein, HAP95](http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077)
14. [FIH Regulates Cellular Metabolism through Hydroxylation of the Deubiquitinase OTUB1](http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077)
15. [Positive regulation of p53 stability and activity by the deubiquitinating enzyme Otubain 1](http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077)
16. [Molecular Basis for the Association of Human E4B U Box Ubiquitin Ligase with E2-Conjugating Enzymes UbcH5c and Ubc4](http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077)
17. [A proteome-scale map of the human interactome network](http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077)
18. [Identification of an unconventional E3 binding surface on the UbcH5 ~ Ub conjugate recognized by a pathogenic bacterial E3 ligase](http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077)
19. [Bifunctional Apoptosis Regulator (BAR), an Endoplasmic Reticulum (ER)-associated E3 Ubiquitin Ligase, Modulates BI-1 Protein Stability and Function in ER Stress](http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077)
20. [The E2 ubiquitin-conjugating enzymes direct polyubiquitination to preferred lysines](http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077)
21. [Structural and functional characterization of the monomeric U-box domain from E4B](http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077)
22. [The IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptor](http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077)
23. [ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity](http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077)
24. [Identification of a human ubiquitin-conjugating enzyme that mediates the E6-AP-dependent ubiquitination of p53](http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077)
25. [Nrdp1-mediated degradation of the gigantic IAP, BRUCE, is a novel pathway for triggering apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077)
26. [MEX is a testis-specific E3 ubiquitin ligase that promotes death receptor-induced apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077)
27. [Priming and Extending: A UbcH5/Cdc34 E2 Handoff Mechanism for Polyubiquitination on a SCF Substrate](http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077)
28. [UBCH7 reactivity profile reveals parkin and HHARI to be RING/HECT hybrids](http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077)
29. [In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077)
30. [High-content genome-wide RNAi screens identify regulators of parkin upstream of mitophagy](http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077)
31. [Human ubiquitin-protein ligase Nedd4: expression, subcellular localization and selective interaction with ubiquitin-conjugating enzymes](http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077)
32. [Identification of a family of closely related human ubiquitin conjugating enzymes](http://www.ebi.ac.uk/QuickGO/annotations?protein=P61077&geneProductId=UniProtKB:P61077)
33. Ensembl Release 99