Ubiquitin-conjugating enzyme, active site
ubiquitin-dependent protein catabolic process
stimulatory C-type lectin receptor signaling pathway
Ubiquitin-conjugating enzyme, active site, protein family
TRIF-dependent toll-like receptor signaling pathway
Identification of a human ubiquitin-conjugating enzyme that mediates the E6-AP-dependent ubiquitination of p53
The E2 ubiquitin-conjugating enzymes direct polyubiquitination to preferred lysines
Members of the E2D (UbcH5) family mediate the ubiquitination of the conserved cysteine of Pex5p, the peroxisomal import receptor
Ubiquitin-conjugating enzyme UBE2D2 is responsible for FBXW2 (F-box and WD repeat domain containing 2)-mediated human GCM1 (glial cell missing homolog 1) ubiquitination and degradation
Molecular basis of Pirh2-mediated p53 ubiquitylation
An altered-specificity ubiquitin-conjugating enzyme/ubiquitin-protein ligase pair
A cancer-associated RING finger protein, RNF43, is a ubiquitin ligase that interacts with a nuclear protein, HAP95
E2~Ub conjugates regulate the kinase activity of Shigella effector OspG during pathogenesis
Structural basis for autoinhibition and phosphorylation-dependent activation of c-Cbl
FIH Regulates Cellular Metabolism through Hydroxylation of the Deubiquitinase OTUB1
Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region
Defining the human deubiquitinating enzyme interaction landscape
Functional proteomics mapping of a human signaling pathway
Positive regulation of p53 stability and activity by the deubiquitinating enzyme Otubain 1
A comprehensive framework of E2-RING E3 interactions of the human ubiquitin-proteasome system
Autoinhibition and phosphorylation-induced activation mechanisms of human cancer and autoimmune disease-related E3 protein Cbl-b
Molecular Basis for the Association of Human E4B U Box Ubiquitin Ligase with E2-Conjugating Enzymes UbcH5c and Ubc4
Crystal structure of UbcH5b~ubiquitin intermediate: insight into the formation of the self-assembled E2~Ub conjugates
Structure of a HOIP/E2~ubiquitin complex reveals RBR E3 ligase mechanism and regulation
Turning the RING domain protein MdmX into an active ubiquitin-protein ligase
Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network
BIRC7–E2 ubiquitin conjugate structure reveals the mechanism of ubiquitin transfer by a RING dimer
Bifunctional Apoptosis Regulator (BAR), an Endoplasmic Reticulum (ER)-associated E3 Ubiquitin Ligase, Modulates BI-1 Protein Stability and Function in ER Stress
Human HRD1 is an E3 ubiquitin ligase involved in degradation of proteins from the endoplasmic reticulum
Activity-enhancing mutations in an E3 ubiquitin ligase identified by high-throughput mutagenesis
Topors functions as an E3 ubiquitin ligase with specific E2 enzymes and ubiquitinates p53
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium