# Ubiquitin conjugating enzyme E2 B

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21135165](https://www.wikidata.org/wiki/Q21135165)  
**Source**: https://4ort.xyz/entity/ubiquitin-conjugating-enzyme-e2-b-q21135165


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P63146)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63146)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P63146&geneProductId=UniProtKB:P63146)
6. [Rad6B is a positive regulator of beta-catenin stabilization](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63146)
7. [Human Cdc34 and Rad6B ubiquitin-conjugating enzymes target repressors of cyclic AMP-induced transcription for proteolysis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63146)
8. [Direct characterization of E2-dependent target specificity and processivity using an artificial p27-linker-E2 ubiquitination system](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63146)
9. [The E2 ubiquitin-conjugating enzymes direct polyubiquitination to preferred lysines](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63146)
10. [ZNF198 protein, involved in rearrangement in myeloproliferative disease, forms complexes with the DNA repair-associated HHR6A/6B and RAD18 proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63146)
11. [A human protein-protein interaction network: a resource for annotating the proteome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63146)
12. [Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63146)
13. [UBR2 mediates transcriptional silencing during spermatogenesis via histone ubiquitination](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63146)
14. [E3 ligase Rad18 promotes monoubiquitination rather than ubiquitin chain formation by E2 enzyme Rad6](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63146)
15. [The human RAD18 gene product interacts with HHR6A and HHR6B](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63146)
16. [Recognition of forked and single-stranded DNA structures by human RAD18 complexed with RAD6B protein triggers its recruitment to stalled replication forks](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63146)
17. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63146)
18. [RAD6-Mediated transcription-coupled H2B ubiquitylation directly stimulates H3K4 methylation in human cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P63146&geneProductId=UniProtKB:P63146)
19. [RAD6-Mediated transcription-coupled H2B ubiquitylation directly stimulates H3K4 methylation in human cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63146)
20. [Localization of two human homologs, HHR6A and HHR6B, of the yeast DNA repair gene RAD6 to chromosomes Xq24-q25 and 5q23-q31](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63146)
21. [RAD6B overexpression confers chemoresistance: RAD6 expression during cell cycle and its redistribution to chromatin during DNA damage-induced response](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63146)
22. [Rad6B is a positive regulator of beta-catenin stabilization](http://www.ebi.ac.uk/QuickGO/annotations?protein=P63146&geneProductId=UniProtKB:P63146)
23. [Novel variants in UBE2B gene and idiopathic male infertility](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63146)
24. [Structural and functional conservation of two human homologs of the yeast DNA repair gene RAD6](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63146)
25. [Human Cdc34 and Rad6B ubiquitin-conjugating enzymes target repressors of cyclic AMP-induced transcription for proteolysis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P63146&geneProductId=UniProtKB:P63146)
26. [Structural and functional conservation of two human homologs of the yeast DNA repair gene RAD6](http://www.ebi.ac.uk/QuickGO/annotations?protein=P63146&geneProductId=UniProtKB:P63146)
27. Ensembl Release 99