# Ubiquilin 2

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21111235](https://www.wikidata.org/wiki/Q21111235)  
**Source**: https://4ort.xyz/entity/ubiquilin-2-q21111235


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q9UHD9)
3. Q20641742
4. [The ubiquitin-like protein PLIC-2 is a negative regulator of G protein-coupled receptor endocytosis.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHD9)
5. [Herp enhances ER-associated protein degradation by recruiting ubiquilins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHD9)
6. [Ubiquilin4 is an adaptor protein that recruits Ubiquilin1 to the autophagy machinery](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHD9)
7. [Ubiquilin-2 (UBQLN2) binds with high affinity to the C-terminal region of TDP-43 and modulates TDP-43 levels in H4 cells: Characterization of inhibition by nucleic acids and 4-aminoquinolines](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHD9)
8. [Pathogenic mutation of UBQLN2 impairs its interaction with UBXD8 and disrupts endoplasmic reticulum-associated protein degradation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHD9)
9. [Proteasome subunit Rpn13 is a novel ubiquitin receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHD9)
10. [ALS-linked mutations in ubiquilin-2 or hnRNPA1 reduce interaction between ubiquilin-2 and hnRNPA1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHD9)
11. [Autoubiquitination of the 26S Proteasome on Rpn13 Regulates Breakdown of Ubiquitin Conjugates](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHD9)
12. [Cross-species divergence of the major recognition pathways of ubiquitylated substrates for ubiquitin/26S proteasome-mediated proteolysis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHD9)
13. [Toward an understanding of the protein interaction network of the human liver](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHD9)
14. [Ubiquitin receptor proteins hHR23a and hPLIC2 interact](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHD9)
15. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHD9)
16. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHD9)
17. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UHD9&geneProductId=UniProtKB:Q9UHD9)
18. [Ubiquilin functions in autophagy and is degraded by chaperone-mediated autophagy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHD9)
19. [Ubiquilin functions in autophagy and is degraded by chaperone-mediated autophagy](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UHD9&geneProductId=UniProtKB:Q9UHD9)
20. [Pathogenic mutation of UBQLN2 impairs its interaction with UBXD8 and disrupts endoplasmic reticulum-associated protein degradation](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UHD9&geneProductId=UniProtKB:Q9UHD9)
21. Ensembl Release 99