# Tyrosine kinase, non-receptor, 2

> mammalian protein found in Mus musculus

**Wikidata**: [Q21981638](https://www.wikidata.org/wiki/Q21981638)  
**Source**: https://4ort.xyz/entity/tyrosine-kinase-non-receptor-2-q21981638


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/O54967)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54967)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=O54967&geneProductId=UniProtKB:O54967)
6. [HECT E3 ubiquitin ligase Nedd4-1 ubiquitinates ACK and regulates epidermal growth factor (EGF)-induced degradation of EGF receptor and ACK](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54967)
7. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54967)
8. [Ack1 mediated AKT/PKB tyrosine 176 phosphorylation regulates its activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54967)
9. [Activated Cdc42-associated kinase 1 is a component of EGF receptor signaling complex and regulates EGF receptor degradation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54967)
10. [Expression, synaptic localization, and developmental regulation of Ack1/Pyk1, a cytoplasmic tyrosine kinase highly expressed in the developing and adult brain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54967)
11. [FGD2, a CDC42-specific exchange factor expressed by antigen-presenting cells, localizes to early endosomes and active membrane ruffles](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54967)
12. [Activation of the nonreceptor protein tyrosine kinase Ack by multiple extracellular stimuli](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54967)
13. [Activated Cdc42 kinase regulates Dock localization in male germ cells during Drosophila spermatogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54967)
14. ensembl Release 96