# Tyrosine hydroxylase

> mammalian protein found in Mus musculus

**Wikidata**: [Q21992242](https://www.wikidata.org/wiki/Q21992242)  
**Source**: https://4ort.xyz/entity/tyrosine-hydroxylase-q21992242


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P24529)
3. Q20641742
4. [Targeted Disruption of the Tyrosine Hydroxylase Locus Results in Severe Catecholamine Depletion and Perinatal Lethality in Mice](http://www.ebi.ac.uk/QuickGO/annotations?protein=P24529&geneProductId=UniProtKB:P24529)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P24529&geneProductId=UniProtKB:P24529)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24529)
7. [Targeted Disruption of the Tyrosine Hydroxylase Locus Results in Severe Catecholamine Depletion and Perinatal Lethality in Mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24529)
8. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24529)
9. [Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system](http://www.ebi.ac.uk/QuickGO/annotations?protein=P24529&geneProductId=UniProtKB:P24529)
10. [Abeta-degrading endopeptidase, neprilysin, in mouse brain: synaptic and axonal localization inversely correlating with Abeta pathology](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24529)
11. [Smoothened controls cyclin D2 expression and regulates the generation of intermediate progenitors in the developing cortex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24529)
12. [Toward the evaluation of function in genetic variability: characterizing human SNP frequencies and establishing BAC-transgenic mice carrying the human CYP1A1_CYP1A2 locus](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24529)
13. [A MicroRNA feedback circuit in midbrain dopamine neurons](http://www.ebi.ac.uk/QuickGO/annotations?protein=P24529&geneProductId=UniProtKB:P24529)
14. [Plexin-a4 mediates axon-repulsive activities of both secreted and transmembrane semaphorins and plays roles in nerve fiber guidance](http://www.ebi.ac.uk/QuickGO/annotations?protein=P24529&geneProductId=UniProtKB:P24529)
15. [Abnormal expression of tyrosine hydroxylase immunoreactivity in cerebellar cortex of ataxic mutant mice](http://www.ebi.ac.uk/QuickGO/annotations?protein=P24529&geneProductId=UniProtKB:P24529)
16. [Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24529)
17. [A MicroRNA feedback circuit in midbrain dopamine neurons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24529)
18. [Plexin-a4 mediates axon-repulsive activities of both secreted and transmembrane semaphorins and plays roles in nerve fiber guidance](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24529)
19. [Abnormal expression of tyrosine hydroxylase immunoreactivity in cerebellar cortex of ataxic mutant mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24529)
20. [Targeted disruption of the tyrosine hydroxylase gene reveals that catecholamines are required for mouse fetal development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24529)
21. [The role of dopamine in learning, memory, and performance of a water escape task](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24529)
22. [Firing properties of dopamine neurons in freely moving dopamine-deficient mice: effects of dopamine receptor activation and anesthesia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24529)
23. [Dopamine controls the firing pattern of dopamine neurons via a network feedback mechanism](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24529)
24. [Dopamine production in the caudate putamen restores feeding in dopamine-deficient mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24529)
25. [Adenosine receptor blockade reverses hypophagia and enhances locomotor activity of dopamine-deficient mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24529)
26. [Ectopic expression of tyrosine hydroxylase in the pigmented epithelium rescues the retinal abnormalities and visual function common in albinos in the absence of melanin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24529)
27. [Dopamine-stimulated sexual behavior is testosterone dependent in mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24529)
28. [A role for dopamine in feeding responses produced by orexigenic agents](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24529)
29. [Dopamine is required for hyperphagia in Lep(ob/ob) mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24529)
30. [Catecholamine synthesis is mediated by tyrosinase in the absence of tyrosine hydroxylase](http://www.ebi.ac.uk/QuickGO/annotations?protein=P24529&geneProductId=UniProtKB:P24529)
31. [Targeted disruption of the tyrosine hydroxylase gene reveals that catecholamines are required for mouse fetal development](http://www.ebi.ac.uk/QuickGO/annotations?protein=P24529&geneProductId=UniProtKB:P24529)
32. [Profound neuronal plasticity in response to inactivation of the dopamine transporter](http://www.ebi.ac.uk/QuickGO/annotations?protein=P24529&geneProductId=UniProtKB:P24529)
33. [Catecholamine synthesis is mediated by tyrosinase in the absence of tyrosine hydroxylase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24529)
34. [Profound neuronal plasticity in response to inactivation of the dopamine transporter](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24529)
35. ensembl Release 106