# Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21131008](https://www.wikidata.org/wiki/Q21131008)  
**Source**: https://4ort.xyz/entity/tyrosine-3-monooxygenase-tryptophan-5-monooxygenase-activation-protein-theta


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P27348)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27348)
5. [The Chediak-Higashi protein interacts with SNARE complex and signal transduction proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27348)
6. [Identification of Mrj, a DnaJ/Hsp40 family protein, as a keratin 8/18 filament regulatory protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27348)
7. [An inflammatory bowel disease-risk variant in INAVA decreases pattern recognition receptor-induced outcomes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27348)
8. [Phosphorylation-dependent binding of 14-3-3 terminates signalling by the Gab2 docking protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27348)
9. [ACBD3 interaction with TBC1 domain 22 protein is differentially affected by enteroviral and kobuviral 3A protein binding](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27348)
10. [SLITRK1 binds 14-3-3 and regulates neurite outgrowth in a phosphorylation-dependent manner](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27348)
11. [Front Signal-Dependent Accumulation of RHOA Inhibitor FAM65B at Leading Edges Polarizes Neutrophils](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27348)
12. [Phosphotyrosine signaling networks in epidermal growth factor receptor overexpressing squamous carcinoma cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27348)
13. [14-3-3 is not essential for Raf-1 function: identification of Raf-1 proteins that are biologically activated in a 14-3-3- and Ras-independent manner](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27348)
14. [Serine phosphorylation of Cbl induced by phorbol ester enhances its association with 14-3-3 proteins in T cells via a novel serine-rich 14-3-3-binding motif](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27348)
15. [Differential protein-protein interactions of LRRK1 and LRRK2 indicate roles in distinct cellular signaling pathways](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27348)
16. [Parkinson-related LRRK2 mutation R1441C/G/H impairs PKA phosphorylation of LRRK2 and disrupts its interaction with 14-3-3](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27348)
17. [A major mutation of KIF21A associated with congenital fibrosis of the extraocular muscles type 1 (CFEOM1) enhances translocation of Kank1 to the membrane](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27348)
18. [Structural basis for protein-protein interactions in the 14-3-3 protein family](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27348)
19. [A Cdc2-related protein kinase hPFTAIRE1 from human brain interacting with 14-3-3 proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27348)
20. [Efficient ADAM22 surface expression is mediated by phosphorylation-dependent interaction with 14-3-3 protein family members](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27348)
21. [The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27348)
22. [Emerging roles for the FSH receptor adapter protein APPL1 and overlap of a putative 14-3-3τ interaction domain with a canonical G-protein interaction site](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27348)
23. [A human MAP kinase interactome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27348)
24. [Regulation of epidermal growth factor receptor trafficking by lysine deacetylase HDAC6](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27348)
25. [Engagement of beta2 integrins recruits 14-3-3 proteins to c-Cbl in human neutrophils](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27348)
26. [Human follitropin receptor (FSHR) interacts with the adapter protein 14-3-3tau](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27348)
27. [Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27348)
28. [The interaction between casein kinase Ialpha and 14-3-3 is phosphorylation dependent](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27348)
29. [Functional specialization of beta-arrestin interactions revealed by proteomic analysis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27348)
30. [14-3-3 binding to LRRK2 is disrupted by multiple Parkinson's disease-associated mutations and regulates cytoplasmic localization](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27348)
31. [Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27348)
32. [Interplay between components of a novel LIM kinase-slingshot phosphatase complex regulates cofilin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27348)
33. [Short 42 degrees C heat shock induces phosphorylation and degradation of Cdc25A which depends on p38MAPK, Chk2 and 14.3.3.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27348)
34. [14-3-3zeta/tau heterodimers regulate Slingshot activity in migrating keratinocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27348)
35. [Perturbation of the mutated EGFR interactome identifies vulnerabilities and resistance mechanisms](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27348)
36. [Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27348)
37. [A proteome-scale map of the human interactome network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27348)
38. [14-3-3 proteins interact with a hybrid prenyl-phosphorylation motif to inhibit G proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27348)
39. [Functional conservation of 14-3-3 isoforms in inhibiting bad-induced apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27348)
40. [Toward an understanding of the protein interaction network of the human liver](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27348)
41. [Kank regulates RhoA-dependent formation of actin stress fibers and cell migration via 14-3-3 in PI3K-Akt signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27348)
42. [Activation-modulated association of 14-3-3 proteins with Cbl in T cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27348)
43. [Progressive degeneration of human neural stem cells caused by pathogenic LRRK2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27348)
44. [The subcellular localization of the ChoRE-binding protein, encoded by the Williams-Beuren syndrome critical region gene 14, is regulated by 14-3-3](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27348)
45. [Defining the membrane proteome of NK cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P27348&geneProductId=UniProtKB:P27348)
46. [Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P27348&geneProductId=UniProtKB:P27348)
47. [Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)](http://www.ebi.ac.uk/QuickGO/annotations?protein=P27348&geneProductId=UniProtKB:P27348)
48. [Large-scale proteomics and phosphoproteomics of urinary exosomes](http://www.ebi.ac.uk/QuickGO/annotations?protein=P27348&geneProductId=UniProtKB:P27348)
49. [MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P27348&geneProductId=UniProtKB:P27348)
50. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P27348&geneProductId=UniProtKB:P27348)