# TYRO protein tyrosine kinase binding protein

> mammalian protein found in Mus musculus

**Wikidata**: [Q21992241](https://www.wikidata.org/wiki/Q21992241)  
**Source**: https://4ort.xyz/entity/tyro-protein-tyrosine-kinase-binding-protein


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/O54885)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=O54885&geneProductId=UniProtKB:O54885)
5. [Characterization of TREM-3, an activating receptor on mouse macrophages: definition of a family of single Ig domain receptors on mouse chromosome 17](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54885)
6. [Integrin signaling in neutrophils and macrophages uses adaptors containing immunoreceptor tyrosine-based activation motifs](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54885)
7. [Ly-49D and Ly-49H associate with mouse DAP12 and form activating receptors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54885)
8. [Rhomboid domain-containing protein 3 is a negative regulator of TLR3-triggered natural killer cell activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54885)
9. [Siglec-15 Protein Regulates Formation of Functional Osteoclasts in Concert with DNAX-activating Protein of 12 kDa (DAP12)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54885)
10. [Identification and characterization of a new pair of immunoglobulin-like receptors LMIR1 and 2 derived from murine bone marrow-derived mast cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54885)
11. [A new triggering receptor expressed on myeloid cells (Trem) family member, Trem-like 4, binds to dead cells and is a DNAX activation protein 12-linked marker for subsets of mouse macrophages and dendritic cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54885)
12. [Paired activating and inhibitory immunoglobulin-like receptors, MAIR-I and MAIR-II, regulate mast cell and macrophage activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54885)
13. [Selective associations with signaling proteins determine stimulatory versus costimulatory activity of NKG2D](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54885)
14. [Signal adaptor DAP10 associates with MDL-1 and triggers osteoclastogenesis in cooperation with DAP12](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54885)
15. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54885)
16. [TREM2 Is a Receptor for β-Amyloid that Mediates Microglial Function.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54885)
17. [OSCAR is a collagen receptor that costimulates osteoclastogenesis in DAP12-deficient humans and mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54885)
18. [Essential role of DAP12 signaling in macrophage programming into a fusion-competent state](http://www.ebi.ac.uk/QuickGO/annotations?protein=O54885&geneProductId=UniProtKB:O54885)
19. [Developmental neuronal death in hippocampus requires the microglial CD11b integrin and DAP12 immunoreceptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54885)
20. [The signaling adapter protein DAP12 regulates multinucleation during osteoclast development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54885)
21. [A DAP12-dependent signal promotes pro-inflammatory polarization in microglia following nerve injury and exacerbates degeneration of injured neurons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54885)
22. [DAP12 couples c-Fms activation to the osteoclast cytoskeleton by recruitment of Syk.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54885)
23. [The immunoreceptor adapter protein DAP12 suppresses B lymphocyte-driven adaptive immune responses.](http://www.ebi.ac.uk/QuickGO/annotations?protein=O54885&geneProductId=UniProtKB:O54885)
24. [Essential role of DAP12 signaling in macrophage programming into a fusion-competent state](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54885)
25. [Impaired synaptic function in the microglial KARAP/DAP12-deficient mouse.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54885)
26. [The immunoreceptor adapter protein DAP12 suppresses B lymphocyte-driven adaptive immune responses.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54885)
27. [Clearance of apoptotic neurons without inflammation by microglial triggering receptor expressed on myeloid cells-2.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54885)
28. ensembl Release 106