Voltage-dependent channel domain superfamily
release of sequestered calcium ion into cytosol
membrane depolarization during action potential
regulation of ion transmembrane transport
mTOR regulates lysosomal ATP-sensitive two-pore Na(+) channels to adapt to metabolic state
Two-pore channels form homo- and heterodimers
Hax-1 identified as a two-pore channel (TPC)-binding protein
Leucine-rich repeat kinase 2 regulates autophagy through a calcium-dependent pathway involving NAADP
NAADP mobilizes calcium from acidic organelles through two-pore channels
Essential requirement for two-pore channel 1 in NAADP-mediated calcium signaling
Dysregulation of lysosomal morphology by pathogenic LRRK2 is corrected by TPC2 inhibition