Twist family bHLH transcription factor 1
type: Thing
description: mammalian protein found in Rattus norvegicus
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P361
  value: Twist-related
additional property: PropertyValue
  property ID: P361
  value: Helix-loop-helix DNA-binding domain superfamily
additional property: PropertyValue
  property ID: P361
  value: Myc-type, basic helix-loop-helix (bHLH) domain, protein family
additional property: PropertyValue
  property ID: P527
  value: Myc-type, basic helix-loop-helix (bHLH) domain
additional property: PropertyValue
  property ID: P637
  value: NP_445982
additional property: PropertyValue
  property ID: P680
  value: DNA-binding transcription factor activity, RNA polymerase II-specific
additional property: PropertyValue
  property ID: P680
  value: molecular function
additional property: PropertyValue
  property ID: P680
  value: DNA-binding transcription factor activity
additional property: PropertyValue
  property ID: P681
  value: nucleus
additional property: PropertyValue
  property ID: P682
  value: negative regulation of transcription by RNA polymerase II
additional property: PropertyValue
  property ID: P682
  value: ossification
additional property: PropertyValue
  property ID: P682
  value: osteoblast differentiation
additional property: PropertyValue
  property ID: P702
  value: Twist1
additional property: PropertyValue
  property ID: P703
  value: brown rat
additional property: PropertyValue
  property ID: P705
  value: ENSRNOP00000014763
confidence:
  popularity graph score:
    score: 0.001
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 10
      unique citations norm: 0.004
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 10
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P352:
    value: Q9EPJ1
    source count: 1
    confidence: 0.2
  P361:
    value: Q24779736
    source count: 1
    confidence: 0.2
    value label: Twist-related
  P361:
    value: Q41797740
    source count: 1
    confidence: 0.2
    value label: Helix-loop-helix DNA-binding domain superfamily
  P361:
    value: Q83146427
    source count: 1
    confidence: 0.2
    value label: Myc-type, basic helix-loop-helix (bHLH) domain, protein family
  P527:
    value: Q24777807
    source count: 1
    confidence: 0.2
    value label: Myc-type, basic helix-loop-helix (bHLH) domain
  P637:
    value: NP_445982
    source count: 1
    confidence: 0.2
  P680:
    value: Q14864645
    source count: 1
    confidence: 0.2
    value label: DNA-binding transcription factor activity, RNA polymerase II-specific
  P680:
    value: Q14860489
    source count: 1
    confidence: 0.2
    value label: molecular function
  P680:
    value: Q14817979
    source count: 1
    confidence: 0.2
    value label: DNA-binding transcription factor activity
  P680:
    value: Q14817982
    source count: 1
    confidence: 0.2
    value label: transcription factor binding
  P680:
    value: Q14860854
    source count: 1
    confidence: 0.2
    value label: protein domain specific binding
  P681:
    value: Q40260
    source count: 2
    confidence: 0.4
    value label: nucleus
  P682:
    value: Q14633878
    source count: 1
    confidence: 0.2
    value label: negative regulation of transcription by RNA polymerase II
  P682:
    value: Q1121544
    source count: 1
    confidence: 0.2
    value label: ossification
  P682:
    value: Q14876609
    source count: 1
    confidence: 0.2
    value label: osteoblast differentiation
  P682:
    value: Q14818001
    source count: 1
    confidence: 0.2
    value label: in utero embryonic development
  P682:
    value: Q14330959
    source count: 1
    confidence: 0.2
    value label: neuron migration
  P702:
    value: Q24418446
    source count: 1
    confidence: 0.2
    value label: Twist1
  P703:
    value: Q184224
    source count: 1
    confidence: 0.2
    value label: brown rat
  P705:
    value: ENSRNOP00000014763
    source count: 1
    confidence: 0.2
citations:
  source: GOA
  stated in qid: Q28018111
  retrieved: 2019-02-14
citations:
  source: Gene expression profiling of pulmonary fibrosis identifies Twist1 as an antiapoptotic molecular "rectifier" of growth factor signaling
  stated in qid: Q28571857
  retrieved: 2019-02-14
citations:
  source: R-twist gene expression during rat palatogenesis
  stated in qid: Q28567889
  retrieved: 2019-02-14
citations:
  source: Twist is a potential oncogene that inhibits apoptosis
  stated in qid: Q24599468
  retrieved: 2019-02-14
citations:
  source: TWIST-1 is overexpressed in neoplastic choroid plexus epithelial cells and promotes proliferation and invasion
  stated in qid: Q28580403
  retrieved: 2019-02-14
citations:
  source: Endochondral and intramembranous fetal bone development: osteoblastic cell proliferation, and expression of alkaline phosphatase, m-twist, and histone H4
  stated in qid: Q28565725
  retrieved: 2019-02-14
citations:
  source: InterPro Release 71.0
  stated in qid: Q58943792
citations:
  source: UniProt
  stated in qid: Q905695
  retrieved: 2022-05-25

source: Q20641742
stated in qid: Q20641742
retrieved: 2022-03-20

source: ensembl Release 106
stated in qid: Q111699881

wikidata id: Q29524362
domain: protein
level: standard
html url: https://4ort.xyz/entity/twist-family-bhlh-transcription-factor-1-q29524362
markdown url: https://4ort.xyz/entity/twist-family-bhlh-transcription-factor-1-q29524362.md
facts url summary: https://4ort.xyz/entity/twist-family-bhlh-transcription-factor-1-q29524362/facts.json
facts url standard: https://4ort.xyz/entity/twist-family-bhlh-transcription-factor-1-q29524362/facts.json
facts url full: https://4ort.xyz/entity/twist-family-bhlh-transcription-factor-1-q29524362/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-02T08:25:21.498118Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T14:00:34.953743+00:00Z