# Twinkle mtDNA helicase

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21443395](https://www.wikidata.org/wiki/Q21443395)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/Twinkle_(protein))  
**Source**: https://4ort.xyz/entity/twinkle-mtdna-helicase


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q96RR1)
3. Q20641742
4. [DNA and RNA binding by the mitochondrial lon protease is regulated by nucleotide and protein substrate](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96RR1)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96RR1)
6. [Twinkle mutations associated with autosomal dominant progressive external ophthalmoplegia lead to impaired helicase function and in vivo mtDNA replication stalling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96RR1)
7. [TWINKLE Has 5' -> 3' DNA helicase activity and is specifically stimulated by mitochondrial single-stranded DNA-binding protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96RR1)
8. [The layered structure of human mitochondrial DNA nucleoids](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96RR1)
9. Ensembl Release 99