# Tumor susceptibility 101

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21114033](https://www.wikidata.org/wiki/Q21114033)  
**Source**: https://4ort.xyz/entity/tumor-susceptibility-101-q21114033


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q99816)
3. Q20641742
4. [DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816)
5. [Divergent retroviral late-budding domains recruit vacuolar protein sorting factors by using alternative adaptor proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816)
7. [Penta-EF-hand protein ALG-2 functions as a Ca2+-dependent adaptor that bridges Alix and TSG101](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816)
8. [Interactions of TOM1L1 with the Multivesicular Body Sorting Machinery](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816)
9. [Distinct functions of human MVB12A and MVB12B in the ESCRT-I dependent on their posttranslational modifications](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816)
10. [Mammalian class E vps proteins recognize ubiquitin and act in the removal of endosomal protein–ubiquitin conjugates](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816)
11. [Tsg101 and the Vacuolar Protein Sorting Pathway Are Essential for HIV-1 Budding](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816)
12. [Formation and release of arrestin domain-containing protein 1-mediated microvesicles (ARMMs) at plasma membrane by recruitment of TSG101 protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816)
13. [Identification of Alix-type and Non-Alix-type ALG-2-binding Sites in Human Phospholipid Scramblase 3](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816)
14. [The Human Endosomal Sorting Complex Required for Transport (ESCRT-I) and Its Role in HIV-1 Budding](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816)
15. [The Protein Network of HIV Budding](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816)
16. [Human ESCRT-II Complex and Its Role in Human Immunodeficiency Virus Type 1 Release](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816)
17. [Differential requirements for Alix and ESCRT-III in cytokinesis and HIV-1 release](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816)
18. [Identification of Human MVB12 Proteins as ESCRT-I Subunits that Function in HIV Budding](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816)
19. [Regulation of Tsg101 Expression by the Steadiness Box: A Role of Tsg101-associated Ligase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816)
20. [Hrs regulates multivesicular body formation via ESCRT recruitment to endosomes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816)
21. [HD-PTP and Alix share some membrane-traffic related proteins that interact with their Bro1 domains or proline-rich regions](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816)
22. [TSG101 interaction with HRS mediates endosomal trafficking and receptor down-regulation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816)
23. [Human ESCRT and ALIX proteins interact with proteins of the midbody and function in cytokinesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816)
24. [Towards a proteome-scale map of the human protein–protein interaction network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816)
25. [A Proteome-Scale Map of the Human Interactome Network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816)
26. [TEX14 Interacts with CEP55 To Block Cell Abscission](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816)
27. [Physical and functional interactions between Daxx and TSG101](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816)
28. [SIMPLE interacts with NEDD4 and TSG101: Evidence for a role in lysosomal sorting and implications for Charcot-Marie-Tooth disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816)
29. [Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816)
30. [An empirical framework for binary interactome mapping](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816)
31. [Pooled‐matrix protein interaction screens using Barcode Fusion Genetics](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816)
32. [Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816)
33. [Spongiform Neurodegeneration-associated E3 Ligase Mahogunin Ubiquitylates TSG101 and Regulates Endosomal Trafficking](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816)
34. [Human ESCRT-II Complex and Its Role in Human Immunodeficiency Virus Type 1 Release](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99816&geneProductId=UniProtKB:Q99816)
35. [Involvement of Vacuolar Protein Sorting Pathway in Ebola Virus Release Independent of TSG101 Interaction](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816)
36. [Nedd4.1-mediated ubiquitination and subsequent recruitment of Tsg101 ensure HTLV-1 Gag trafficking towards the multivesicular body pathway prior to virus budding](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816)
37. [In‐depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99816&geneProductId=UniProtKB:Q99816)
38. [Identification and proteomic profiling of exosomes in human urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99816&geneProductId=UniProtKB:Q99816)
39. [Collection, storage, preservation, and normalization of human urinary exosomes for biomarker discovery](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99816&geneProductId=UniProtKB:Q99816)
40. [Monitoring the Rab27 associated exosome pathway using nanoparticle tracking analysis](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99816&geneProductId=UniProtKB:Q99816)
41. [Large-Scale Proteomics and Phosphoproteomics of Urinary Exosomes](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99816&geneProductId=UniProtKB:Q99816)
42. [Proteomic analysis of podocyte exosome-enriched fraction from normal human urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99816&geneProductId=UniProtKB:Q99816)
43. [Membrane budding and scission by the ESCRT machinery: it's all in the neck](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816)
44. [The role of ESCRT proteins in fusion events involving lysosomes, endosomes and autophagosomes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816)
45. [UBAP1 Is a Component of an Endosome-Specific ESCRT-I Complex that Is Essential for MVB Sorting](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816)
46. [Structural basis for membrane targeting by the MVB12-associated β-prism domain of the human ESCRT-I MVB12 subunit](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816)
47. [Collection, storage, preservation, and normalization of human urinary exosomes for biomarker discovery](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816)
48. [Monitoring the Rab27 associated exosome pathway using nanoparticle tracking analysis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816)
49. [Identification and proteomic profiling of exosomes in human urine](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816)
50. [Large-Scale Proteomics and Phosphoproteomics of Urinary Exosomes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816)