# Tumor suppressor ARF

> human protein (annotated by UniProtKB/Swiss-Prot Q8N726)

**Wikidata**: [Q7117832](https://www.wikidata.org/wiki/Q7117832)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/P14arf)  
**Source**: https://4ort.xyz/entity/tumor-suppressor-arf


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q8N726)
3. [Swiss-Prot](http://www.uniprot.org/uniprot/P42771.txt?version=179)
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N726)
5. [ARF Promotes MDM2 Degradation and Stabilizes p53: ARF-INK4a Locus Deletion Impairs Both the Rb and p53 Tumor Suppression Pathways](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8N726&geneProductId=UniProtKB:Q8N726)
6. [PTEN regulation by Akt-EGR1-ARF-PTEN axis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N726)
7. [A novel ARF-binding protein (LZAP) alters ARF regulation of HDM2](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8N726&geneProductId=UniProtKB:Q8N726)
8. [Tumor suppressor ARF promotes non-classic proteasome-independent polyubiquitination of COMMD1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N726)
9. [Transcription-independent ARF regulation in oncogenic stress-mediated p53 responses](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N726)
10. [GLTSCR2 promotes the nucleoplasmic translocation and subsequent degradation of nucleolar ARF](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N726)
11. [EBV-encoded EBNA-5 associates with P14ARF in extranucleolar inclusions and prolongs the survival of P14ARF-expressing cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N726)
12. [The autophagic inducer smARF interacts with and is stabilized by the mitochondrial p32 protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N726)
13. [Antiviral action of the tumor suppressor ARF](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N726)
14. [Bidirectional autoregulatory mechanism of metastasis-associated protein 1-alternative reading frame pathway in oncogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N726)
15. [p14ARF interacts with N-Myc and inhibits its transcriptional activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N726)
16. [14-3-3 Binding to Pim-phosphorylated Ser166 and Ser186 of human Mdm2--Potential interplay with the PKB/Akt pathway and p14(ARF)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N726)
17. [A human interactome in three quantitative dimensions organized by stoichiometries and abundances](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N726)
18. [p14ARF interacts with DAXX: effects on HDM2 and p53](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N726)
19. [ARF-BP1/Mule is a critical mediator of the ARF tumor suppressor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N726)
20. [A CDKN2A mutation in familial melanoma that abrogates binding of p16INK4a to CDK4 but not CDK6](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N726)
21. [ARF-dependent regulation of ATM and p53 associated KZNF (Apak) protein activity in response to oncogenic stress](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N726)
22. [A novel putative collaborator of p19ARF](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N726)
23. [A novel nuclear interactor of ARF and MDM2 (NIAM) that maintains chromosomal stability](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N726)
24. [p14 Arf promotes small ubiquitin-like modifier conjugation of Werners helicase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N726)
25. [Peptides derived from two dynamically disordered proteins self-assemble into amyloid-like fibrils](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N726)
26. [Cooperation between the ribosomal proteins L5 and L11 in the p53 pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N726)
27. [Mutations in human ARF exon 2 disrupt its nucleolar localization and impair its ability to block nuclear export of MDM2 and p53](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8N726&geneProductId=UniProtKB:Q8N726)
28. [A novel proapoptotic gene PANO encodes a post-translational modulator of the tumor suppressor p14ARF](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N726)
29. [Short Mitochondrial ARF Triggers Parkin/PINK1-dependent Mitophagy](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8N726&geneProductId=UniProtKB:Q8N726)
30. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8N726&geneProductId=UniProtKB:Q8N726)
31. [Immunohistochemical analysis of p18INK4C and p14ARF protein expression in 117 oligodendrogliomas: correlation with tumor grade and clinical outcome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N726)
32. [p14ARF induces G2 cell cycle arrest in p53- and p21-deficient cells by down-regulating p34cdc2 kinase activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N726)
33. [Ribosomal protein S7 as a novel modulator of p53-MDM2 interaction: binding to MDM2, stabilization of p53 protein, and activation of p53 function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N726)
34. [Activation of p53 by MEG3 non-coding RNA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N726)
35. [Immortalization of human mammary epithelial cells is associated with inactivation of the p14ARF-p53 pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N726)
36. [Adenovirus-mediated overexpression of p14(ARF) induces p53 and Bax-independent apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N726)
37. [ARF Promotes MDM2 Degradation and Stabilizes p53: ARF-INK4a Locus Deletion Impairs Both the Rb and p53 Tumor Suppression Pathways](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N726)
38. BabelNet
39. [OpenAlex](https://docs.openalex.org/download-snapshot/snapshot-data-format)