# Tumor suppressor ARF

> mouse protein (annotated by UniProtKB/Swiss-Prot Q64364)

**Wikidata**: [Q21499012](https://www.wikidata.org/wiki/Q21499012)  
**Source**: https://4ort.xyz/entity/tumor-suppressor-arf-q21499012


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q64364)
3. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64364)
4. [Structural polymorphism in the N-terminal oligomerization domain of NPM1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64364)
5. [CARF is a novel protein that cooperates with mouse p19ARF (human p14ARF) in activating p53](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64364)
6. [Association of p19(ARF) with Mdm2 inhibits ubiquitin ligase activity of Mdm2 for tumor suppressor p53.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64364)
7. [Genetic inactivation of the transcription factor TIF-IA leads to nucleolar disruption, cell cycle arrest, and p53-mediated apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64364)
8. [ARF impedes NPM/B23 shuttling in an Mdm2-sensitive tumor suppressor pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64364)
9. [Domain-specific c-Myc ubiquitylation controls c-Myc transcriptional and apoptotic activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64364)
10. [The ARF tumor suppressor inhibits BCL6-mediated transcriptional repression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64364)
11. [Bidirectional autoregulatory mechanism of metastasis-associated protein 1-alternative reading frame pathway in oncogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64364)
12. [The autophagic inducer smARF interacts with and is stabilized by the mitochondrial p32 protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64364)
13. [Pex19p dampens the p19ARF-p53-p21WAF1 tumor suppressor pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64364)
14. [Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64364)
15. [Cloning and characterization of murine p16INK4a and p15INK4b genes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64364)
16. [Cyclin D-cdk4 activity modulates the subnuclear localization and interaction of MEF2 with SRC-family coactivators during skeletal muscle differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64364)
17. [Defining the molecular basis of Arf and Hdm2 interactions](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64364)
18. [Nucleophosmin is required for DNA integrity and p19Arf protein stability](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64364)
19. [Nucleophosmin and its AML-associated mutant regulate c-Myc turnover through Fbw7 gamma](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64364)
20. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64364&geneProductId=UniProtKB:Q64364)
21. [CARF is a novel protein that cooperates with mouse p19ARF (human p14ARF) in activating p53](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64364&geneProductId=UniProtKB:Q64364)
22. [Ink4a and Arf differentially affect cell proliferation and neural stem cell self-renewal in Bmi1-deficient mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64364)
23. [Hmga2 promotes neural stem cell self-renewal in young but not old mice by reducing p16Ink4a and p19Arf Expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64364)
24. [Effect of 9p21.3 coronary artery disease locus neighboring genes on atherosclerosis in mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64364)
25. [The ink4a/arf tumor suppressors cooperate with p21cip1/waf in the processes of mouse epidermal differentiation, senescence, and carcinogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64364)
26. [Nucleophosmin serves as a rate-limiting nuclear export chaperone for the Mammalian ribosome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64364)
27. [p19ARF determines the balance between normal cell proliferation rate and apoptosis during mammary gland development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64364)
28. [PTEN regulation by Akt-EGR1-ARF-PTEN axis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64364)
29. [The Fbx4 Tumor Suppressor Regulates Cyclin D1 Accumulation and Prevents Neoplastic Transformation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64364)
30. [c-Abl promotes osteoblast expansion by differentially regulating canonical and non-canonical BMP pathways and p16INK4a expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64364)
31. [Apoptosis triggered by Myc-induced suppression of Bcl-X(L) or Bcl-2 is bypassed during lymphomagenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64364)
32. [A novel zinc finger protein Zfp277 mediates transcriptional repression of the Ink4a/arf locus through polycomb repressive complex 1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64364)