# tumor protein p73

> mammalian protein found in Homo sapiens

**Wikidata**: [Q4197146](https://www.wikidata.org/wiki/Q4197146)  
**Source**: https://4ort.xyz/entity/tumor-protein-p73


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/O15350)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15350)
5. [A novel response element confers p63- and p73-specific activation of the WNT4 promoter](http://www.ebi.ac.uk/QuickGO/annotations?protein=O15350&geneProductId=UniProtKB:O15350)
6. [A novel response element confers p63- and p73-specific activation of the WNT4 promoter](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15350)
7. [Brn-3a/POU4F1 interacts with and differentially affects p73-mediated transcription](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15350)
8. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=O15350&geneProductId=UniProtKB:O15350)
9. [ASPP1 and ASPP2: common activators of p53 family members](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15350)
10. [The F-box protein FBXO45 promotes the proteasome-dependent degradation of p73](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15350)
11. [Yap1 phosphorylation by c-Abl is a critical step in selective activation of proapoptotic genes in response to DNA damage](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15350)
12. [MDM2 and MDMX bind and stabilize the p53-related protein p73](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15350)
13. [Biochemical and structural studies of ASPP proteins reveal differential binding to p53, p63, and p73](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15350)
14. [Runt-related transcription factor 2 attenuates the transcriptional activity as well as DNA damage-mediated induction of pro-apoptotic TAp73 to regulate chemosensitivity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15350)
15. [Molecular basis of the interactions between the p73 N terminus and p300: effects on transactivation and modulation by phosphorylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15350)
16. [The Nedd4-binding partner 1 (N4BP1) protein is an inhibitor of the E3 ligase Itch](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15350)
17. [Ligand binding to WW tandem domains of YAP2 transcriptional regulator is under negative cooperativity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15350)
18. [The ubiquitin-protein ligase Itch regulates p73 stability](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15350)
19. [Aurora Kinase-A Inactivates DNA Damage-Induced Apoptosis and Spindle Assembly Checkpoint Response Functions of p73](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15350)
20. [Differential control of TAp73 and DeltaNp73 protein stability by the ring finger ubiquitin ligase PIR2.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15350)
21. [Differential Effect of ik3-1/Cables on p53- and p73-induced Cell Death](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15350)
22. [SIRT1 interacts with p73 and suppresses p73-dependent transcriptional activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15350)
23. [Apoptotic function of human PMS2 compromised by the nonsynonymous single-nucleotide polymorphic variant R20Q](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15350)
24. [Structure of p73 DNA-binding domain tetramer modulates p73 transactivation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15350)
25. [Structural evolution of p53, p63, and p73: Implication for heterotetramer formation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15350)
26. [Plk3 inhibits pro-apoptotic activity of p73 through physical interaction and phosphorylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15350)
27. [Inhibitory role of Plk1 in the regulation of p73-dependent apoptosis through physical interaction and phosphorylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15350)
28. [Functional interplay between MDM2, p63/p73 and mutant p53](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15350)
29. [A common polymorphism acts as an intragenic modifier of mutant p53 behaviour](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15350)
30. [A census of human transcription factors: function, expression and evolution](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15350)
31. [DRAGO (KIAA0247), a new DNA damage-responsive, p53-inducible gene that cooperates with p53 as oncosuppressor. [Corrected]](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15350)
32. [p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15350)
33. [Directed expression of dominant-negative p73 enables proliferation of cardiomyocytes in mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15350)
34. [The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15350)
35. [Physical and functional interaction between HCV core protein and the different p73 isoforms](http://www.ebi.ac.uk/QuickGO/annotations?protein=O15350&geneProductId=UniProtKB:O15350)
36. Ensembl Release 99
37. [Identifiers.org](https://registry.identifiers.org/registry/uniprot)
38. UMLS 2023