# tumor protein p63

> mammalian protein found in Homo sapiens

**Wikidata**: [Q7671094](https://www.wikidata.org/wiki/Q7671094)  
**Source**: https://4ort.xyz/entity/tumor-protein-p63


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q9H3D4)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9H3D4&geneProductId=UniProtKB:Q9H3D4)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4)
6. [ASPP1 and ASPP2: common activators of p53 family members](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4)
7. [HIPK2 phosphorylates ΔNp63α and promotes its degradation in response to DNA damage.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4)
8. [Biochemical and structural studies of ASPP proteins reveal differential binding to p53, p63, and p73](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4)
9. [PKCδ stabilizes TAp63 to promote cell apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4)
10. [Identification of DeltaNp63alpha protein interactions by mass spectrometry](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4)
11. [The E3 ubiquitin ligase Itch controls the protein stability of p63](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4)
12. [A Pin1/mutant p53 axis promotes aggressiveness in breast cancer](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4)
13. [Toward an understanding of the protein interaction network of the human liver](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4)
14. [A Mutant-p53/Smad complex opposes p63 to empower TGFbeta-induced metastasis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4)
15. [Stxbp4 regulates DeltaNp63 stability by suppression of RACK1-dependent degradation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4)
16. [A new human p53 homologue](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4)
17. [A C-terminal inhibitory domain controls the activity of p63 by an intramolecular mechanism](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4)
18. [DNA damage in oocytes induces a switch of the quality control factor TAp63α from dimer to tetramer](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4)
19. [Structural evolution of p53, p63, and p73: Implication for heterotetramer formation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4)
20. [Structures of p63 DNA binding domain in complexes with half-site and with spacer-containing full response elements](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4)
21. [NIR, an inhibitor of histone acetyltransferases, regulates transcription factor TAp63 and is controlled by the cell cycle](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9H3D4&geneProductId=UniProtKB:Q9H3D4)
22. [Functional interplay between MDM2, p63/p73 and mutant p53](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4)
23. [A census of human transcription factors: function, expression and evolution](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4)
24. [Expression of the p53 homologue p63alpha and deltaNp63alpha in normal and neoplastic cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4)
25. [p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4)
26. [p63 is a prostate basal cell marker and is required for prostate development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4)
27. [Stxbp4 regulates DeltaNp63 stability by suppression of RACK1-dependent degradation](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9H3D4&geneProductId=UniProtKB:Q9H3D4)
28. [The p53 family member genes are involved in the Notch signal pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4)
29. [Cloning and functional analysis of human p51, which structurally and functionally resembles p53](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4)
30. [p73 and p63 are homotetramers capable of weak heterotypic interactions with each other but not with p53](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4)
31. [Hepatocyte growth factor (HGF) and 1,25-dihydroxyvitamin D together stimulate human bone marrow-derived stem cells toward the osteogenic phenotype by HGF-induced up-regulation of VDR](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4)
32. [Complex transcriptional effects of p63 isoforms: identification of novel activation and repression domains](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4)
33. [A novel response element confers p63- and p73-specific activation of the WNT4 promoter](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H3D4)
34. Ensembl Release 99