# Tumor protein p53

> mammalian protein found in Rattus norvegicus

**Wikidata**: [Q28563060](https://www.wikidata.org/wiki/Q28563060)  
**Source**: https://4ort.xyz/entity/tumor-protein-p53-q28563060


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P10361)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10361)
5. [Analysis of p53 and NF-κB signaling in modulating the cardiomyocyte fate during hypertrophy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10361)
6. [Physical and functional interaction between WT1 and p53 proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10361)
7. [A nucleolar mechanism controlling cell proliferation in stem cells and cancer cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10361)
8. [Polyamine depletion induces nucleophosmin modulating stability and transcriptional activity of p53 in intestinal epithelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10361)
9. [Stabilization and activation of p53 by the coactivator protein TAFII31](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10361)
10. [Ubiquitin-dependent degradation of p53 protein despite phosphorylation at its N terminus by acetaminophen](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10361)
11. [Combinatorial control of the bradykinin B2 receptor promoter by p53, CREB, KLF-4, and CBP: implications for terminal nephron differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10361)
12. [Caveolin-1/PTRF upregulation constitutes a mechanism for mediating p53-induced cellular senescence: implications for evidence-based therapy of delayed wound healing in diabetes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10361)
13. [Hindlimb unloading increases muscle content of cytosolic but not nuclear Id2 and p53 proteins in young adult and aged rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10361)
14. [Multiple apoptotic pathways induced by p53-dependent acidification in benzo[a]pyrene-exposed hepatic F258 cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10361)
15. [Mutant ubiquitin found in Alzheimer's disease causes neuritic beading of mitochondria in association with neuronal degeneration](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10361)
16. [Effect of ischemic preconditioning on mitochondrial dysfunction and mitochondrial p53 translocation after transient global cerebral ischemia in rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10361)
17. [Inhibition of p53 by pifithrin-alpha reduces myocyte apoptosis and leukocyte transmigration in aged rat hearts following 24 hours of reperfusion](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10361)
18. [Polyamine depletion stabilizes p53 resulting in inhibition of normal intestinal epithelial cell proliferation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10361)
19. [Oxidative stress regulates IGF1R expression in vascular smooth-muscle cells via p53 and HDAC recruitment](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10361)
20. [Age-dependent upregulation of p53 and cytochrome c release and susceptibility to apoptosis in skeletal muscle fiber of aged rats: role of carnitine and lipoic acid](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10361)
21. [p53 expression and apoptosis in the lens after ultraviolet radiation exposure](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10361)
22. [p53 reaction to apoptosis induced by hydroxyapatite nanoparticles in rat macrophages](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10361)
23. [Apoptosis and inhibition of gap-junctional intercellular communication induced by LA-12, a novel hydrophobic platinum(IV) complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10361)
24. [A novel animal model to investigate fractionated radiotherapy-induced alimentary mucositis: the role of apoptosis, p53, nuclear factor-kappaB, COX-1, and COX-2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10361)
25. [Kinetics of GADD45α, TP53 and CASP3 gene expression in the rat lens in vivo in response to exposure to double threshold dose of UV-B radiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10361)
26. [Cilostazol protects rat chondrocytes against nitric oxide-induced apoptosis in vitro and prevents cartilage destruction in a rat model of osteoarthritis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10361)
27. [Clusterin regulates β-amyloid toxicity via Dickkopf-1-driven induction of the wnt-PCP-JNK pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10361)
28. [Differentially expressed pro- and anti-apoptogenic genes in response to benzene exposure: Immunohistochemical localization of p53, Bag, Bad, Bax, Bcl-2, and Bcl-w in lung epithelia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10361)
29. [Activation of p53 signaling initiates apoptotic death in a cellular model of Parkinson's disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10361)
30. [Retinoic acid downregulates microRNAs to induce abnormal development of spinal cord in spina bifida rat model](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10361)
31. [Niacin deficiency alters p53 expression and impairs etoposide-induced cell cycle arrest and apoptosis in rat bone marrow cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10361)
32. [IFN-gamma promotes apoptosis of the uterus and placenta in pregnant rat and human cytotrophoblast cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10361)
33. [Hyperthermia-induced apoptosis in two rat yolk sac tumor cell lines with different radiothermosensitivity in vitro](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10361)
34. [Role of reactive oxygen species in p53 activation during cisplatin-induced apoptosis of rat mesangial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10361)
35. [Hyperbaric oxygen attenuates apoptosis and decreases inflammation in an ischemic wound model](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10361)
36. [Glutamine supplementation prevents exercise-induced neutrophil apoptosis and reduces p38 MAPK and JNK phosphorylation and p53 and caspase 3 expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10361)
37. [Activation of p53 enhances apoptosis and insulin resistance in a rat model of alcoholic liver disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10361)
38. [Activation of the p53-p21(Cip1) pathway is required for CDK2 activation and S-phase entry in primary rat hepatocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10361)
39. [Induction of p53 by GKLF is essential for inhibition of proliferation of vascular smooth muscle cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10361)
40. [p53 initiates apoptosis by transcriptionally targeting the antiapoptotic protein ARC](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10361)
41. [Nupr1/Chop signal axis is involved in mitochondrion-related endothelial cell apoptosis induced by methamphetamine](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10361)
42. ensembl Release 106