# Tsc1 Dmel_CG6147

> protein found in Drosophila melanogaster

**Wikidata**: [Q29818026](https://www.wikidata.org/wiki/Q29818026)  
**Source**: https://4ort.xyz/entity/tsc1-dmel-cg6147


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q9VCC9)
3. Q20641742
4. [Tsc tumour suppressor proteins antagonize amino-acid-TOR signalling](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VCC9&geneProductId=UniProtKB:Q9VCC9)
5. [Rheb is a direct target of the tuberous sclerosis tumour suppressor proteins](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VCC9&geneProductId=UniProtKB:Q9VCC9)
6. [Control of growth and organ size in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VCC9&geneProductId=UniProtKB:Q9VCC9)
7. [A systematic screen for tube morphogenesis and branching genes in the Drosophila tracheal system.](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VCC9&geneProductId=UniProtKB:Q9VCC9)
8. [The Drosophila tuberous sclerosis complex gene homologs restrict cell growth and cell proliferation](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VCC9&geneProductId=UniProtKB:Q9VCC9)
9. [Mechanisms of size control.](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VCC9&geneProductId=UniProtKB:Q9VCC9)
10. [Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VCC9&geneProductId=UniProtKB:Q9VCC9)
11. [The class III PI(3)K Vps34 promotes autophagy and endocytosis but not TOR signaling in Drosophila.](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VCC9&geneProductId=UniProtKB:Q9VCC9)
12. [Rheb fills a GAP between TSC and TOR.](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VCC9&geneProductId=UniProtKB:Q9VCC9)
13. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VCC9&geneProductId=UniProtKB:Q9VCC9)
14. [Relationship between growth arrest and autophagy in midgut programmed cell death in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VCC9&geneProductId=UniProtKB:Q9VCC9)
15. [TSC1/2 regulates intestinal stem cell maintenance and lineage differentiation through Rheb-TORC1-S6K but independently of nutritional status or Notch regulation](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VCC9&geneProductId=UniProtKB:Q9VCC9)
16. [Platelet-derived growth factor/vascular endothelial growth factor receptor inactivation by sunitinib results in Tsc1/Tsc2-dependent inhibition of TORC1](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VCC9&geneProductId=UniProtKB:Q9VCC9)
17. [Tuberous Sclerosis Complex 1 Regulates dE2F1 Expression during Development and Cooperates with RBF1 to Control Proliferation and Survival](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VCC9&geneProductId=UniProtKB:Q9VCC9)
18. [Dynamic switch of negative feedback regulation in Drosophila Akt-TOR signaling](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VCC9&geneProductId=UniProtKB:Q9VCC9)
19. [A Drosophila Genome-Wide Screen Identifies Regulators of Steroid Hormone Production and Developmental Timing](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VCC9&geneProductId=UniProtKB:Q9VCC9)
20. [Tor signalling in bugs, brain and brawn](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VCC9&geneProductId=UniProtKB:Q9VCC9)
21. [Insulin/IGF and target of rapamycin signaling: a TOR de force in growth control](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VCC9&geneProductId=UniProtKB:Q9VCC9)
22. [A role for p38 stress-activated protein kinase in regulation of cell growth via TORC1.](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VCC9&geneProductId=UniProtKB:Q9VCC9)
23. [TSC1 and TSC2 tumor suppressors antagonize insulin signaling in cell growth](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VCC9&geneProductId=UniProtKB:Q9VCC9)
24. [The TORC1 inhibitors Nprl2 and Nprl3 mediate an adaptive response to amino-acid starvation in Drosophila.](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VCC9&geneProductId=UniProtKB:Q9VCC9)
25. [Temporal control of differentiation by the insulin receptor/tor pathway in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VCC9&geneProductId=UniProtKB:Q9VCC9)
26. [Nutritional control of protein biosynthetic capacity by insulin via Myc in Drosophila.](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VCC9&geneProductId=UniProtKB:Q9VCC9)
27. [Specialized hepatocyte-like cells regulate Drosophila lipid metabolism.](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VCC9&geneProductId=UniProtKB:Q9VCC9)
28. [An RNA interference screen identifies a novel regulator of target of rapamycin that mediates hypoxia suppression of translation in Drosophila S2 cells.](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VCC9&geneProductId=UniProtKB:Q9VCC9)
29. [Role of autophagy in glycogen breakdown and its relevance to chloroquine myopathy](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VCC9&geneProductId=UniProtKB:Q9VCC9)
30. [LST8 regulates cell growth via target-of-rapamycin complex 2 (TORC2).](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VCC9&geneProductId=UniProtKB:Q9VCC9)
31. [Spatial Activation of TORC1 Is Regulated by Hedgehog and E2F1 Signaling in the Drosophila Eye.](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VCC9&geneProductId=UniProtKB:Q9VCC9)
32. [A genetic screen identifies Tor as an interactor of VAPB in a Drosophila model of amyotrophic lateral sclerosis.](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VCC9&geneProductId=UniProtKB:Q9VCC9)
33. [Sestrin as a Feedback Inhibitor of TOR That Prevents Age-Related Pathologies](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VCC9&geneProductId=UniProtKB:Q9VCC9)
34. ensembl Release 106