# TSC complex subunit 1

> mammalian protein found in Mus musculus

**Wikidata**: [Q14908117](https://www.wikidata.org/wiki/Q14908117)  
**Source**: https://4ort.xyz/entity/tsc-complex-subunit-1-q14908117


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q9EP53)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EP53)
5. [The TSC1 tumour suppressor hamartin regulates cell adhesion through ERM proteins and the GTPase Rho](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EP53)
6. [p53 target genes sestrin1 and sestrin2 connect genotoxic stress and mTOR signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EP53)
7. [Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EP53)
8. [Insulin like growth factor-1-induced phosphorylation and altered distribution of tuberous sclerosis complex (TSC)1/TSC2 in C2C12 myotubes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EP53)
9. [Tumor suppressor Tsc1 is a new Hsp90 co-chaperone that facilitates folding of kinase and non-kinase clients.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EP53)
10. [Regulation of neuronal morphology and function by the tumor suppressors Tsc1 and Tsc2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EP53)
11. [TSC2 missense mutations inhibit tuberin phosphorylation and prevent formation of the tuberin-hamartin complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EP53)
12. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EP53)
13. [In-depth protein profiling of the postsynaptic density from mouse hippocampus using data-independent acquisition proteomics](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EP53)
14. [Tsc1 promotes the differentiation of memory CD8+ T cells via orchestrating the transcriptional and metabolic programs](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EP53)
15. [A mouse model of tuberous sclerosis 1 showing background specific early post-natal mortality and metastatic renal cell carcinoma](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EP53)
16. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9EP53&geneProductId=UniProtKB:Q9EP53)
17. [A germ-line Tsc1 mutation causes tumor development and embryonic lethality that are similar, but not identical to, those caused by Tsc2 mutation in mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EP53)
18. [A mouse model of tuberous sclerosis: neuronal loss of Tsc1 causes dysplastic and ectopic neurons, reduced myelination, seizure activity, and limited survival](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EP53)
19. [Epileptogenesis and reduced inward rectifier potassium current in tuberous sclerosis complex-1-deficient astrocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EP53)
20. [The tuberous sclerosis complex regulates trafficking of glucose transporters and glucose uptake](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EP53)
21. [Loss of tuberous sclerosis complex 1 (Tsc1) expression results in increased Rheb/S6K pathway signaling important for astrocyte cell size regulation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EP53)
22. [Glutathione metabolism in long-living Ames dwarf mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EP53)
23. ensembl Release 106