# TRPV6

> protein-coding gene in the species Homo sapiens

**Wikidata**: [Q14891586](https://www.wikidata.org/wiki/Q14891586)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/TRPV6)  
**Source**: https://4ort.xyz/entity/trpv6


## References

1. ensembl Release 106
2. NCBI homo sapiens annotation release 107
3. Q20641742
4. Online Mendelian Inheritance in Man
5. HomoloGene build68
6. [Orthologous MAtrix](https://omabrowser.org/oma/vps/Q9H1D0/)
7. UniProt
8. Calcium selective channel TRPV6: Structure, function, and implications in health and disease
9. TRPV6 plays a new role in predicting survival of patients with esophageal squamous cell carcinoma
10. The role of TRPV6 in breast carcinogenesis
11. Calcium channel TRPV6 as a potential therapeutic target in estrogen receptor-negative breast cancer.
12. High expression of transient receptor potential channels in human breast cancer epithelial cells and tissues: correlation with pathological parameters.
13. TRP calcium channel and breast cancer: expression, role and correlation with clinical parameters
14. An automated epifluorescence microscopy imaging assay for the identification of phospho-AKT level modulators in breast cancer cells
15. Expression and functionality of TRPV1 in breast cancer cells
16. Chemical inhibitors of the calcium entry channel TRPV6.
17. Regulation of calcium influx and signaling pathway in cancer cells via TRPV6-Numb1 interaction.
18. Suppression of aberrant transient receptor potential cation channel, subfamily V, member 6 expression in hyperproliferative colonic crypts by dietary calcium
19. Human PXR-mediated induction of intestinal CYP3A4 attenuates 1α,25-dihydroxyvitamin D₃ function in human colon adenocarcinoma LS180 cells
20. Role of proinflammatory cytokines on expression of vitamin D metabolism and target genes in colon cancer cells
21. Calcium deficiency-induced and TRP channel-regulated IGF1R-PI3K-Akt signaling regulates abnormal epithelial cell proliferation
22. Variants That Affect Function of Calcium Channel TRPV6 Are Associated With Early-Onset Chronic Pancreatitis
23. TRPV6 as A Target for Cancer Therapy
24. TRPV6 mediates capsaicin-induced apoptosis in gastric cancer cells--Mechanisms behind a possible new "hot" cancer treatment
25. Generation and analysis of the thiazide-sensitive Na+-Cl− cotransporter (Ncc/Slc12a3) Ser707X knockin mouse as a model of Gitelman syndrome
26. A family of calcium-permeable channels in the kidney: distinct roles in renal calcium handling
27. Mechanisms for Hypercalciuria in Pseudohypoaldosteronism Type II-Causing WNK4 Knock-In Mice
28. Mechanisms and regulation of epithelial Ca2+ absorption in health and disease
29. Mutations in the vitamin D receptor and hereditary vitamin D-resistant rickets
30. Capsaicin induces apoptosis in human small cell lung cancer via the TRPV6 receptor and the calpain pathway
31. Expression and Prognostic Roles of TRPV5 and TRPV6 in Non-Small Cell Lung Cancer after Curative Resection
32. Kefir improves bone mass and microarchitecture in an ovariectomized rat model of postmenopausal osteoporosis
33. Quercetin Enhances VDR Activity, Leading to Stimulation of Its Target Gene Expression in Caco-2 Cells
34. Advanced oxidation protein products decrease the expression of calcium transport channels in small intestinal epithelium via the p44/42 MAPK signaling pathway
35. (Patho)physiological implications of the novel epithelial Ca2+ channels TRPV5 and TRPV6.
36. Vitamin D: molecular mechanism of action
37. Molecular mechanisms of vitamin D action
38. Calcium Metabolism and Correcting Calcium Deficiencies
39. Molecular aspects of intestinal calcium absorption
40. Calcium-selective ion channel, CaT1, is apically localized in gastrointestinal tract epithelia and is aberrantly expressed in human malignancies
41. In vivo detection of human TRPV6-rich tumors with anti-cancer peptides derived from soricidin
42. Inhibition of Transient Receptor Potential Vanilloid 6 channel, elevated in human ovarian cancers, reduces tumour growth in a xenograft model
43. TRPV6 modulates proliferation of human pancreatic neuroendocrine BON-1 tumour cells.
44. Expression and prognostic significance of TRPV6 in the development and progression of pancreatic cancer.
45. First-in-human phase I study of SOR-C13, a TRPV6 calcium channel inhibitor, in patients with advanced solid tumors
46. TRPV6 as a Putative Genomic Susceptibility Locus Influencing Racial Disparities in Cancer
47. TRPV6: From identification to function
48. The role of the TRPV6 channel in cancer.
49. TRP channels in prostate cancer: the good, the bad and the ugly?
50. TRPV6 and prostate cancer: cancer growth beyond the prostate correlates with increased TRPV6 Ca2+ channel expression