# Troponin T2, cardiac type

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21104681](https://www.wikidata.org/wiki/Q21104681)  
**Source**: https://4ort.xyz/entity/troponin-t2-cardiac-type


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P45379)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45379)
5. [Ca2+, pH and the regulation of cardiac myofilament force and ATPase activity](http://www.ebi.ac.uk/QuickGO/annotations?protein=P45379&geneProductId=UniProtKB:P45379)
6. [Cardiac troponin T isoforms affect the Ca2+ sensitivity and inhibition of force development. Insights into the role of troponin T isoforms in the heart](http://www.ebi.ac.uk/QuickGO/annotations?protein=P45379&geneProductId=UniProtKB:P45379)
7. [A proteome-scale map of the human interactome network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45379)
8. [Alpha-tropomyosin and cardiac troponin T mutations cause familial hypertrophic cardiomyopathy: a disease of the sarcomere](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45379)
9. [Investigation of a truncated cardiac troponin T that causes familial hypertrophic cardiomyopathy: Ca(2+) regulatory properties of reconstituted thin filaments depend on the ratio of mutant to wild-type protein](http://www.ebi.ac.uk/QuickGO/annotations?protein=P45379&geneProductId=UniProtKB:P45379)
10. [Severe disease expression of cardiac troponin C and T mutations in patients with idiopathic dilated cardiomyopathy](http://www.ebi.ac.uk/QuickGO/annotations?protein=P45379&geneProductId=UniProtKB:P45379)
11. [Alpha-tropomyosin and cardiac troponin T mutations cause familial hypertrophic cardiomyopathy: a disease of the sarcomere](http://www.ebi.ac.uk/QuickGO/annotations?protein=P45379&geneProductId=UniProtKB:P45379)
12. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P45379&geneProductId=UniProtKB:P45379)
13. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45379)
14. [Investigation of a truncated cardiac troponin T that causes familial hypertrophic cardiomyopathy: Ca(2+) regulatory properties of reconstituted thin filaments depend on the ratio of mutant to wild-type protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45379)
15. [Severe disease expression of cardiac troponin C and T mutations in patients with idiopathic dilated cardiomyopathy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45379)
16. [Alterations in thin filament regulation induced by a human cardiac troponin T mutant that causes dilated cardiomyopathy are distinct from those induced by troponin T mutants that cause hypertrophic cardiomyopathy](http://www.ebi.ac.uk/QuickGO/annotations?protein=P45379&geneProductId=UniProtKB:P45379)
17. [Single-gene mutations and increased left ventricular wall thickness in the community: the Framingham Heart Study](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45379)
18. [Alterations in thin filament regulation induced by a human cardiac troponin T mutant that causes dilated cardiomyopathy are distinct from those induced by troponin T mutants that cause hypertrophic cardiomyopathy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45379)
19. [A novel phosphorylation site, Serine 199, in the C-terminus of cardiac troponin I regulates calcium sensitivity and susceptibility to calpain-induced proteolysis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45379)
20. [Dilated cardiomyopathy mutations in three thin filament regulatory proteins result in a common functional phenotype](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45379)
21. [A novel phosphorylation site, Serine 199, in the C-terminus of cardiac troponin I regulates calcium sensitivity and susceptibility to calpain-induced proteolysis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P45379&geneProductId=UniProtKB:P45379)
22. Ensembl Release 99