# Troponin C1, slow skeletal and cardiac type

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21124649](https://www.wikidata.org/wiki/Q21124649)  
**Source**: https://4ort.xyz/entity/troponin-c1-slow-skeletal-and-cardiac-type-q21124649


## References

1. UniProt
2. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL2051955)
3. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P63316)
4. Q20641742
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P63316&geneProductId=UniProtKB:P63316)
6. [Structure of the core domain of human cardiac troponin in the Ca(2+)-saturated form](http://www.ebi.ac.uk/QuickGO/annotations?protein=P63316&geneProductId=UniProtKB:P63316)
7. [Tryptophan mutants of cardiac troponin C: 3D structure, troponin I affinity, and in situ activity](http://www.ebi.ac.uk/QuickGO/annotations?protein=P63316&geneProductId=UniProtKB:P63316)
8. [Tryptophan mutants of cardiac troponin C: 3D structure, troponin I affinity, and in situ activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63316)
9. [Alpha-tropomyosin and cardiac troponin T mutations cause familial hypertrophic cardiomyopathy: a disease of the sarcomere](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63316)
10. [Severe disease expression of cardiac troponin C and T mutations in patients with idiopathic dilated cardiomyopathy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63316)
11. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63316)
12. [Overexpression of human cardiac troponin-I and troponin-C in Escherichia coli and their purification and characterisation. Two point mutations allow high-level expression of troponin-I](http://www.ebi.ac.uk/QuickGO/annotations?protein=P63316&geneProductId=UniProtKB:P63316)
13. [Altered regulatory properties of human cardiac troponin I mutants that cause hypertrophic cardiomyopathy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63316)
14. [LuTHy: a double-readout bioluminescence-based two-hybrid technology for quantitative mapping of protein-protein interactions in mammalian cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63316)
15. [Toward an understanding of the protein interaction network of the human liver](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63316)
16. [Structure of the core domain of human cardiac troponin in the Ca(2+)-saturated form](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63316)
17. [Overexpression of human cardiac troponin-I and troponin-C in Escherichia coli and their purification and characterisation. Two point mutations allow high-level expression of troponin-I](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63316)
18. [Functional Consequences of the Mutations in Human Cardiac Troponin I Gene Found in Familial Hypertrophic Cardiomyopathy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63316)
19. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63316)
20. [Investigation of a truncated cardiac troponin T that causes familial hypertrophic cardiomyopathy: Ca(2+) regulatory properties of reconstituted thin filaments depend on the ratio of mutant to wild-type protein](http://www.ebi.ac.uk/QuickGO/annotations?protein=P63316&geneProductId=UniProtKB:P63316)
21. [Cardiac troponin T isoforms affect the Ca2+ sensitivity and inhibition of force development. Insights into the role of troponin T isoforms in the heart](http://www.ebi.ac.uk/QuickGO/annotations?protein=P63316&geneProductId=UniProtKB:P63316)
22. [A novel phosphorylation site, Serine 199, in the C-terminus of cardiac troponin I regulates calcium sensitivity and susceptibility to calpain-induced proteolysis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63316)
23. [Investigation of a truncated cardiac troponin T that causes familial hypertrophic cardiomyopathy: Ca(2+) regulatory properties of reconstituted thin filaments depend on the ratio of mutant to wild-type protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63316)
24. [Cardiac troponin T isoforms affect the Ca2+ sensitivity and inhibition of force development. Insights into the role of troponin T isoforms in the heart](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63316)
25. [Cloning, structural analysis, and expression of the human slow twitch skeletal muscle/cardiac troponin C gene](http://www.ebi.ac.uk/QuickGO/annotations?protein=P63316&geneProductId=UniProtKB:P63316)
26. [Cloning, structural analysis, and expression of the human slow twitch skeletal muscle/cardiac troponin C gene](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63316)
27. Ensembl Release 99