# Tropomyosin 1

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21105496](https://www.wikidata.org/wiki/Q21105496)  
**Source**: https://4ort.xyz/entity/tropomyosin-1


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P09493)
3. Q20641742
4. [Nebulette interacts with filamin C](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09493)
5. [Extracellular signal-regulated kinase mediates phosphorylation of tropomyosin-1 to promote cytoskeleton remodeling in response to oxidative stress: impact on membrane blebbing](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09493)
6. [A proteome-scale map of the human interactome network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09493)
7. [Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09493)
8. [Next-generation sequencing to generate interactome datasets](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09493)
9. [Towards a proteome-scale map of the human protein–protein interaction network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09493)
10. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09493)
11. [Alpha-tropomyosin and cardiac troponin T mutations cause familial hypertrophic cardiomyopathy: a disease of the sarcomere](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09493)
12. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P09493&geneProductId=UniProtKB:P09493)
13. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09493)
14. [Single-gene mutations and increased left ventricular wall thickness in the community: the Framingham Heart Study](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09493)
15. [Proteomics of human umbilical vein endothelial cells applied to etoposide-induced apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09493)
16. [Human hTM alpha gene: expression in muscle and nonmuscle tissue](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09493)
17. [Hypertrophic cardiomyopathy caused by a novel alpha-tropomyosin mutation (V95A) is associated with mild cardiac phenotype, abnormal calcium binding to troponin, abnormal myosin cycling, and poor prognosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09493)
18. [MicroRNA-21 Regulates Vascular Smooth Muscle Cell Function via Targeting Tropomyosin 1 in Arteriosclerosis Obliterans of Lower Extremities](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09493)
19. [Silencing of the Tropomyosin-1 gene by DNA methylation alters tumor suppressor function of TGF-beta](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09493)
20. [Role of high-molecular weight tropomyosins in TGF-beta-mediated control of cell motility](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09493)
21. [Mutations that alter the surface charge of alpha-tropomyosin are associated with dilated cardiomyopathy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09493)
22. [Dilated cardiomyopathy mutant tropomyosin mice develop cardiac dysfunction with significantly decreased fractional shortening and myofilament calcium sensitivity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09493)
23. [Hypertrophic cardiomyopathy caused by a novel alpha-tropomyosin mutation (V95A) is associated with mild cardiac phenotype, abnormal calcium binding to troponin, abnormal myosin cycling, and poor prognosis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P09493&geneProductId=UniProtKB:P09493)
24. Ensembl Release 99