# Tropomyosin 1

> mammalian protein found in Rattus norvegicus

**Wikidata**: [Q28559550](https://www.wikidata.org/wiki/Q28559550)  
**Source**: https://4ort.xyz/entity/tropomyosin-1-q28559550


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P04692)
3. Q20641742
4. [Four fibroblast tropomyosin isoforms are expressed from the rat alpha-tropomyosin gene via alternative RNA splicing and the use of two promoters](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04692)
5. [Local destabilization of the tropomyosin coiled coil gives the molecular flexibility required for actin binding](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04692)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04692)
7. [Effect of actin C-terminal modification on tropomyosin isoforms binding and thin filament regulation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04692)
8. [In vitro formation and characterization of the skeletal muscle α·β tropomyosin heterodimers](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04692)
9. [Specificity of dimer formation in tropomyosins: influence of alternatively spliced exons on homodimer and heterodimer assembly](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04692)
10. [Thermal unfolding of smooth muscle and nonmuscle tropomyosin alpha-homodimers with alternatively spliced exons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04692)
11. [Structural requirements of tropomodulin for tropomyosin binding and actin filament capping](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04692)
12. [Importance of internal regions and the overall length of tropomyosin for actin binding and regulatory function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04692)
13. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04692)
14. [Structure and tropomyosin binding properties of the N-terminal capping domain of tropomodulin 1.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04692)
15. [Identification of a multiprotein "motor" complex binding to water channel aquaporin-2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04692)
16. [Hypertrophic cardiomyopathy caused by a novel alpha-tropomyosin mutation (V95A) is associated with mild cardiac phenotype, abnormal calcium binding to troponin, abnormal myosin cycling, and poor prognosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04692)
17. [Silencing of the Tropomyosin-1 gene by DNA methylation alters tumor suppressor function of TGF-beta](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04692)
18. [Role of high-molecular weight tropomyosins in TGF-beta-mediated control of cell motility](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04692)
19. [Medium perfusion enables engineering of compact and contractile cardiac tissue](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04692)
20. ensembl Release 106