# Tripartite motif containing 5

> mammalian protein found in Homo sapiens

**Wikidata**: [Q408249](https://www.wikidata.org/wiki/Q408249)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/TRIM5alpha)  
**Source**: https://4ort.xyz/entity/tripartite-motif-containing-5


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q9C035)
3. Q20641742
4. Freebase Data Dumps. 2013
5. [TRIM proteins regulate autophagy and can target autophagic substrates by direct recognition](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9C035)
6. [The tripartite motif family identifies cell compartments](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9C035)
7. [TRIM5 is an innate immune sensor for the retrovirus capsid lattice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9C035)
8. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9C035)
9. [TRIM5α associates with proteasomal subunits in cells while in complex with HIV-1 virions](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9C035)
10. [p62/sequestosome-1 associates with and sustains the expression of retroviral restriction factor TRIM5alpha](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9C035)
11. [PKD1 phosphorylation-dependent degradation of SNAIL by SCF-FBXO11 regulates epithelial-mesenchymal transition and metastasis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9C035)
12. [Systematic Analysis of Dimeric E3-RING Interactions Reveals Increased Combinatorial Complexity in Human Ubiquitination Networks](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9C035)
13. [TRIM27 negatively regulates NOD2 by ubiquitination and proteasomal degradation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9C035)
14. [TRIM E3 ligases interfere with early and late stages of the retroviral life cycle](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9C035)
15. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9C035&geneProductId=UniProtKB:Q9C035)
16. [Unique features of TRIM5alpha among closely related human TRIM family members](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9C035&geneProductId=UniProtKB:Q9C035)
17. [TRIM protein-mediated regulation of inflammatory and innate immune signaling and its association with antiretroviral activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9C035)
18. [TRIM5α and Species Tropism of HIV/SIV](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9C035)
19. Ensembl Release 99
20. Identifiers.org