# Trinucleotide repeat containing adaptor 6C

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21111275](https://www.wikidata.org/wiki/Q21111275)  
**Source**: https://4ort.xyz/entity/trinucleotide-repeat-containing-adaptor-6c-q21111275


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q9HCJ0)
3. Q20641742
4. [Two PABPC1-binding sites in GW182 proteins promote miRNA-mediated gene silencing](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCJ0)
5. [Phosphorylation at intrinsically disordered regions of PAM2 motif-containing proteins modulates their interactions with PABPC1 and influences mRNA fate](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCJ0)
6. [GW182 proteins directly recruit cytoplasmic deadenylase complexes to miRNA targets](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCJ0)
7. [Structural insights into the human GW182-PABC interaction in microRNA-mediated deadenylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCJ0)
8. [miRNA-mediated deadenylation is orchestrated by GW182 through two conserved motifs that interact with CCR4-NOT](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCJ0)
9. [Structural basis of binding of P-body-associated proteins GW182 and ataxin-2 by the Mlle domain of poly(A)-binding protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCJ0)
10. [GW182 proteins cause PABP dissociation from silenced miRNA targets in the absence of deadenylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCJ0)
11. [Ago-TNRC6 triggers microRNA-mediated decay by promoting two deadenylation steps](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCJ0)
12. [Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCJ0)
13. [The C-terminal domains of human TNRC6A, TNRC6B, and TNRC6C silence bound transcripts independently of Argonaute proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCJ0)
14. [A DDX6-CNOT1 complex and W-binding pockets in CNOT9 reveal direct links between miRNA target recognition and silencing](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCJ0)
15. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCJ0)
16. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCJ0)
17. [miRNA-mediated deadenylation is orchestrated by GW182 through two conserved motifs that interact with CCR4-NOT](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HCJ0&geneProductId=UniProtKB:Q9HCJ0)
18. [The interactions of GW182 proteins with PABP and deadenylases are required for both translational repression and degradation of miRNA targets](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HCJ0&geneProductId=UniProtKB:Q9HCJ0)
19. [miRNA repression involves GW182-mediated recruitment of CCR4-NOT through conserved W-containing motifs](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCJ0)
20. [The interactions of GW182 proteins with PABP and deadenylases are required for both translational repression and degradation of miRNA targets](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCJ0)
21. Ensembl Release 99