# Triggering receptor expressed on myeloid cells 2

> mammalian protein found in Mus musculus

**Wikidata**: [Q21991310](https://www.wikidata.org/wiki/Q21991310)  
**Source**: https://4ort.xyz/entity/triggering-receptor-expressed-on-myeloid-cells-2-q21991310


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q99NH8)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99NH8)
5. [TREM-2 binds to lipooligosaccharides of Neisseria gonorrhoeae and is expressed on reproductive tract epithelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99NH8)
6. [Pattern recognition by TREM-2: binding of anionic ligands](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99NH8)
7. [Osteoprotection by semaphorin 3A](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99NH8)
8. [Cutting edge: inflammatory responses can be triggered by TREM-1, a novel receptor expressed on neutrophils and monocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99NH8)
9. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99NH8&geneProductId=UniProtKB:Q99NH8)
10. [TREM2 Is a Receptor for β-Amyloid that Mediates Microglial Function.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99NH8)
11. [TREM2 shedding by cleavage at the H157-S158 bond is accelerated for the Alzheimer's disease-associated H157Y variant](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99NH8)
12. [A new triggering receptor expressed on myeloid cells (Trem) family member, Trem-like 4, binds to dead cells and is a DNAX activation protein 12-linked marker for subsets of mouse macrophages and dendritic cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99NH8)
13. [OSCAR is a collagen receptor that costimulates osteoclastogenesis in DAP12-deficient humans and mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99NH8)
14. [Essential role of DAP12 signaling in macrophage programming into a fusion-competent state](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99NH8)
15. [microRNA-34a-Mediated Down-Regulation of the Microglial-Enriched Triggering Receptor and Phagocytosis-Sensor TREM2 in Age-Related Macular Degeneration](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99NH8)
16. [TREM2 Maintains Microglial Metabolic Fitness in Alzheimer's Disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99NH8)
17. [TREM2 deficiency attenuates neuroinflammation and protects against neurodegeneration in a mouse model of tauopathy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99NH8)
18. [TREM2 deficiency impairs chemotaxis and microglial responses to neuronal injury.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99NH8)
19. [TREM2 deficiency impairs chemotaxis and microglial responses to neuronal injury.](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99NH8&geneProductId=UniProtKB:Q99NH8)
20. [Clearance of apoptotic neurons without inflammation by microglial triggering receptor expressed on myeloid cells-2.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99NH8)
21. [TREM2 protects against cerebral ischemia/reperfusion injury](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99NH8)
22. [TREM2, a DAP12-associated receptor, regulates osteoclast differentiation and function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99NH8)
23. ensembl Release 106