# Transporter 2, ATP binding cassette subfamily B member

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21106706](https://www.wikidata.org/wiki/Q21106706)  
**Source**: https://4ort.xyz/entity/transporter-2-atp-binding-cassette-subfamily-b-member


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q03519)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03519)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03519&geneProductId=UniProtKB:Q03519)
6. [ABC-me: a novel mitochondrial transporter induced by GATA-1 during erythroid differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03519)
7. [HLA-F is a predominantly empty, intracellular, TAP-associated MHC class Ib protein with a restricted expression pattern](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03519)
8. [Assembly and function of the two ABC transporter proteins encoded in the human major histocompatibility complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03519)
9. [TAP- and tapasin-dependent HLA-E surface expression correlates with the binding of an MHC class I leader peptide](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03519)
10. [The varicellovirus UL49.5 protein blocks the transporter associated with antigen processing (TAP) by inhibiting essential conformational transitions in the 6+6 transmembrane TAP core complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03519)
11. [Specific targeting of the EBV lytic phase protein BNLF2a to the transporter associated with antigen processing results in impairment of HLA class I-restricted antigen presentation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03519)
12. [A mechanism of viral immune evasion revealed by cryo-EM analysis of the TAP transporter](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03519)
13. [The first N-terminal transmembrane helix of each subunit of the antigenic peptide transporter TAP is essential for independent tapasin binding](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03519)
14. [Varicelloviruses avoid T cell recognition by UL49.5-mediated inactivation of the transporter associated with antigen processing](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03519)
15. [Structural arrangement of the transmission interface in the antigen ABC transport complex TAP.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03519)
16. [Tapasin interacts with the membrane-spanning domains of both TAP subunits and enhances the structural stability of TAP1 x TAP2 Complexes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03519)
17. [Redox regulation facilitates optimal peptide selection by MHC class I during antigen processing](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03519)
18. [Detection of TAP family dimerizations by an in vivo assay in mammalian cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03519&geneProductId=UniProtKB:Q03519)
19. [Assembly and function of the two ABC transporter proteins encoded in the human major histocompatibility complex](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03519&geneProductId=UniProtKB:Q03519)
20. [Assembly, Intracellular Localization, and Nucleotide Binding Properties of the Human Peptide Transporters TAP1 and TAP2 Expressed by Recombinant Vaccinia Viruses](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03519)
21. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03519)
22. [Assembly, Intracellular Localization, and Nucleotide Binding Properties of the Human Peptide Transporters TAP1 and TAP2 Expressed by Recombinant Vaccinia Viruses](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03519&geneProductId=UniProtKB:Q03519)
23. [Detection of TAP family dimerizations by an in vivo assay in mammalian cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03519)
24. [Molecular architecture of the TAP-associated MHC class I peptide-loading complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03519)
25. [Defining the membrane proteome of NK cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03519&geneProductId=UniProtKB:Q03519)
26. [Multiple regions of the transporter associated with antigen processing (TAP) contribute to its peptide binding site](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03519&geneProductId=UniProtKB:Q03519)
27. [Defining the membrane proteome of NK cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03519)
28. [Multiple regions of the transporter associated with antigen processing (TAP) contribute to its peptide binding site](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03519)
29. [An epitope-selective, transporter associated with antigen presentation (TAP)-1/2-independent pathway and a more general TAP-1/2-dependent antigen-processing pathway allow recognition of the HIV-1 envelope glycoprotein by CD8+ CTL](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03519)
30. [Presentation of numerous viral peptides to mouse major histocompatibility complex (MHC) class I-restricted T lymphocytes is mediated by the human MHC-encoded transporter or by a hybrid mouse-human transporter](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03519)
31. Ensembl Release 99
32. UMLS 2023
33. Transporter Classification database