# Transmembrane serine protease 2

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21126599](https://www.wikidata.org/wiki/Q21126599)  
**Source**: https://4ort.xyz/entity/transmembrane-serine-protease-2


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/O15393)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15393)
5. [Cloning of the TMPRSS2 gene, which encodes a novel serine protease with transmembrane, LDLRA, and SRCR domains and maps to 21q22.3](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15393)
6. [A transmembrane serine protease is linked to the severe acute respiratory syndrome coronavirus receptor and activates virus entry](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15393)
7. [Proteomic analysis of podocyte exosome-enriched fraction from normal human urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=O15393&geneProductId=UniProtKB:O15393)
8. [Large-scale proteomics and phosphoproteomics of urinary exosomes](http://www.ebi.ac.uk/QuickGO/annotations?protein=O15393&geneProductId=UniProtKB:O15393)
9. [Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)](http://www.ebi.ac.uk/QuickGO/annotations?protein=O15393&geneProductId=UniProtKB:O15393)
10. [In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=O15393&geneProductId=UniProtKB:O15393)
11. [In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15393)
12. [Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15393)
13. [Large-scale proteomics and phosphoproteomics of urinary exosomes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15393)
14. [TMPRSS2 and ADAM17 cleave ACE2 differentially and only proteolysis by TMPRSS2 augments entry driven by the severe acute respiratory syndrome coronavirus spike protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15393)
15. [A transmembrane serine protease is linked to the severe acute respiratory syndrome coronavirus receptor and activates virus entry](http://www.ebi.ac.uk/QuickGO/annotations?protein=O15393&geneProductId=UniProtKB:O15393)
16. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15393)
17. Ensembl Release 99
18. [Source](https://www.guidetopharmacology.org/coronavirus.jsp)