# transmembrane protein 173

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21112990](https://www.wikidata.org/wiki/Q21112990)  
**Source**: https://4ort.xyz/entity/transmembrane-protein-173


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q86WV6)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86WV6)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q86WV6&geneProductId=UniProtKB:Q86WV6)
6. [Cyclic di-GMP sensing via the innate immune signaling protein STING](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q86WV6&geneProductId=UniProtKB:Q86WV6)
7. [Cyclic di-GMP sensing via the innate immune signaling protein STING](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86WV6)
8. [ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86WV6)
9. [The ubiquitin ligase TRIM56 regulates innate immune responses to intracellular double-stranded DNA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86WV6)
10. [The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86WV6)
11. [ISG56 is a negative-feedback regulator of virus-triggered signaling and cellular antiviral response](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86WV6)
12. [STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86WV6)
13. [NLRC3, a Member of the NLR Family of Proteins, Is a Negative Regulator of Innate Immune Signaling Induced by the DNA Sensor STING](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86WV6)
14. [Tetraspanin 6 (TSPAN6) Negatively Regulates Retinoic Acid-inducible Gene I-like Receptor-mediated Immune Signaling in a Ubiquitination-dependent Manner](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86WV6)
15. [Activation of STAT6 by STING is critical for antiviral innate immunity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86WV6)
16. [Mapping a dynamic innate immunity protein interaction network regulating type I interferon production](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86WV6)
17. [IFI16 is an innate immune sensor for intracellular DNA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86WV6)
18. [Quantitative Proteomics Identified TTC4 as a TBK1 Interactor and a Positive Regulator of SeV-induced Innate Immunity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86WV6)
19. [Hepatitis C virus NS4B protein targets STING and abrogates RIG-I-mediated type I interferon-dependent innate immunity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86WV6)
20. [DNA tumor virus oncogenes antagonize the cGAS-STING DNA-sensing pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86WV6)
21. [Hepatitis C virus NS4B blocks the interaction of STING and TBK1 to evade host innate immunity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86WV6)
22. [WDR5 is essential for assembly of the VISA-associated signaling complex and virus-triggered IRF3 and NF-kappaB activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86WV6)
23. [Crystal structures of STING protein reveal basis for recognition of cyclic di-GMP](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86WV6)
24. [Structure of STING bound to cyclic di-GMP reveals the mechanism of cyclic dinucleotide recognition by the immune system](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86WV6)
25. [The structural basis for the sensing and binding of cyclic di-GMP by STING](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86WV6)
26. [Rat and human STINGs profile similarly towards anticancer/antiviral compounds](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q86WV6&geneProductId=UniProtKB:Q86WV6)
27. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86WV6)
28. [Rat and human STINGs profile similarly towards anticancer/antiviral compounds](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86WV6)
29. [ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q86WV6&geneProductId=UniProtKB:Q86WV6)
30. [RNF26 Temporally Regulates Virus-Triggered Type I Interferon Induction by Two Distinct Mechanisms](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q86WV6&geneProductId=UniProtKB:Q86WV6)
31. [RNF26 Temporally Regulates Virus-Triggered Type I Interferon Induction by Two Distinct Mechanisms](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86WV6)
32. [The ubiquitin ligase TRIM56 regulates innate immune responses to intracellular double-stranded DNA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q86WV6&geneProductId=UniProtKB:Q86WV6)
33. [The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q86WV6&geneProductId=UniProtKB:Q86WV6)
34. ensembl Release 95