# Transmembrane protein 173

> mammalian protein found in Mus musculus

**Wikidata**: [Q21495187](https://www.wikidata.org/wiki/Q21495187)  
**Source**: https://4ort.xyz/entity/transmembrane-protein-173-q21495187


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q3TBT3)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3TBT3)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q3TBT3&geneProductId=UniProtKB:Q3TBT3)
6. [Ancient Origin of cGAS-STING Reveals Mechanism of Universal 2′,3′ cGAMP Signaling](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q3TBT3&geneProductId=UniProtKB:Q3TBT3)
7. [STING is a direct innate immune sensor of cyclic di-GMP](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q3TBT3&geneProductId=UniProtKB:Q3TBT3)
8. [NLRC3, a Member of the NLR Family of Proteins, Is a Negative Regulator of Innate Immune Signaling Induced by the DNA Sensor STING](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3TBT3)
9. [The helicase DDX41 senses intracellular DNA mediated by the adaptor STING in dendritic cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3TBT3)
10. [Activation of STAT6 by STING Is Critical for Antiviral Innate Immunity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3TBT3)
11. [The helicase DDX41 recognizes the bacterial secondary messengers cyclic di-GMP and cyclic di-AMP to activate a type I interferon immune response](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3TBT3)
12. [The Ubiquitin Ligase TRIM56 Regulates Innate Immune Responses to Intracellular Double-Stranded DNA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3TBT3)
13. [Cyclic GMP-AMP Is an Endogenous Second Messenger in Innate Immune Signaling by Cytosolic DNA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q3TBT3&geneProductId=UniProtKB:Q3TBT3)
14. [Rat and human STINGs profile similarly towards anticancer/antiviral compounds](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q3TBT3&geneProductId=UniProtKB:Q3TBT3)
15. [STING is a direct innate immune sensor of cyclic di-GMP](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3TBT3)
16. [Ancient Origin of cGAS-STING Reveals Mechanism of Universal 2′,3′ cGAMP Signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3TBT3)
17. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3TBT3)
18. [Cyclic GMP-AMP Is an Endogenous Second Messenger in Innate Immune Signaling by Cytosolic DNA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3TBT3)
19. [Rat and human STINGs profile similarly towards anticancer/antiviral compounds](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3TBT3)
20. [Atg9a controls dsDNA-driven dynamic translocation of STING and the innate immune response](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3TBT3)
21. [STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q3TBT3&geneProductId=UniProtKB:Q3TBT3)
22. [LSm14A is a processing body-associated sensor of viral nucleic acids that initiates cellular antiviral response in the early phase of viral infection](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3TBT3)
23. [STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3TBT3)
24. [ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q3TBT3&geneProductId=UniProtKB:Q3TBT3)
25. [The helicase DDX41 senses intracellular DNA mediated by the adaptor STING in dendritic cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q3TBT3&geneProductId=UniProtKB:Q3TBT3)
26. [ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3TBT3)
27. [Trex1 regulates lysosomal biogenesis and interferon-independent activation of antiviral genes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3TBT3)
28. [Chronic innate immune activation of TBK1 suppresses mTORC1 activity and dysregulates cellular metabolism](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3TBT3)
29. ensembl Release 95