# Transient receptor potential cation channel subfamily V member 4

> mammalian protein found in Homo sapiens

**Wikidata**: [Q7671500](https://www.wikidata.org/wiki/Q7671500)  
**Source**: https://4ort.xyz/entity/transient-receptor-potential-cation-channel-subfamily-v-member-4-q7671500


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q9HBA0)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HBA0)
5. [An Orally Active TRPV4 Channel Blocker Prevents and Resolves Pulmonary Edema Induced by Heart Failure](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HBA0)
6. [Ca2+-dependent Potentiation of the Nonselective Cation Channel TRPV4 Is Mediated by a C-terminal Calmodulin Binding Site](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HBA0)
7. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HBA0&geneProductId=UniProtKB:Q9HBA0)
8. [An aquaporin-4/transient receptor potential vanilloid 4 (AQP4/TRPV4) complex is essential for cell-volume control in astrocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HBA0)
9. [Human TRPV4 channel splice variants revealed a key role of ankyrin domains in multimerization and trafficking](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HBA0)
10. [Regulation of a transient receptor potential (TRP) channel by tyrosine phosphorylation. SRC family kinase-dependent tyrosine phosphorylation of TRPV4 on TYR-253 mediates its response to hypotonic stress](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HBA0)
11. [Functional coupling of TRPV4 cationic channel and large conductance, calcium-dependent potassium channel in human bronchial epithelial cell lines](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HBA0&geneProductId=UniProtKB:Q9HBA0)
12. [Interaction between the Linker, Pre-S1, and TRP Domains Determines Folding, Assembly, and Trafficking of TRPV Channels](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HBA0)
13. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HBA0)
14. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HBA0&geneProductId=UniProtKB:Q9HBA0)
15. [Functional coupling of TRPV4 cationic channel and large conductance, calcium-dependent potassium channel in human bronchial epithelial cell lines](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HBA0)
16. [OTRPC4, a nonselective cation channel that confers sensitivity to extracellular osmolarity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HBA0)
17. [TRPV4 channel is involved in the coupling of fluid viscosity changes to epithelial ciliary activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HBA0)
18. [Ca2+-dependent Potentiation of the Nonselective Cation Channel TRPV4 Is Mediated by a C-terminal Calmodulin Binding Site](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HBA0&geneProductId=UniProtKB:Q9HBA0)
19. [An Orally Active TRPV4 Channel Blocker Prevents and Resolves Pulmonary Edema Induced by Heart Failure](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HBA0&geneProductId=UniProtKB:Q9HBA0)
20. [A mutation in TRPV4 results in altered chondrocyte calcium signaling in severe metatropic dysplasia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HBA0)
21. Ensembl Release 99
22. Identifiers.org