Transient receptor potential cation channel, subfamily V, member 1
type: Thing
description: mammalian protein found in Mus musculus
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P129
  value: 2-aminoethoxydiphenylborate
additional property: PropertyValue
  property ID: P129
  value: capsaicin
additional property: PropertyValue
  property ID: P361
  value: Transient receptor potential cation channel subfamily V member 1
additional property: PropertyValue
  property ID: P361
  value: Ankyrin repeat-containing domain superfamily
additional property: PropertyValue
  property ID: P361
  value: Ion transport domain, protein family
additional property: PropertyValue
  property ID: P527
  value: ankyrin repeat-containing domain
additional property: PropertyValue
  property ID: P527
  value: Ion transport domain
additional property: PropertyValue
  property ID: P527
  value: ankyrin repeat
additional property: PropertyValue
  property ID: P637
  value: NP_001001445
additional property: PropertyValue
  property ID: P680
  value: nucleotide binding
additional property: PropertyValue
  property ID: P680
  value: cation transmembrane transporter activity
additional property: PropertyValue
  property ID: P680
  value: ion channel activity
additional property: PropertyValue
  property ID: P681
  value: cell projection
additional property: PropertyValue
  property ID: P681
  value: membrane
additional property: PropertyValue
  property ID: P681
  value: dendritic spine membrane
additional property: PropertyValue
  property ID: P682
  value: cellular response to nerve growth factor stimulus
additional property: PropertyValue
  property ID: P682
  value: urinary bladder smooth muscle contraction
additional property: PropertyValue
  property ID: P682
  value: detection of chemical stimulus involved in sensory perception of pain
additional property: PropertyValue
  property ID: P702
  value: Trpv1
additional property: PropertyValue
  property ID: P703
  value: house mouse
additional property: PropertyValue
  property ID: P705
  value: ENSMUSP00000099585
additional property: PropertyValue
  property ID: P705
  value: ENSMUSP00000006106
additional property: PropertyValue
  property ID: P705
  value: ENSMUSP00000104110
confidence:
  popularity graph score:
    score: 0.004
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 27
      unique citations norm: 0.011
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 27
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P129:
    value: Q4596857
    source count: 1
    confidence: 0.2
    value label: 2-aminoethoxydiphenylborate
  P129:
    value: Q273169
    source count: 1
    confidence: 0.2
    value label: capsaicin
  P352:
    value: Q704Y3
    source count: 1
    confidence: 0.2
  P361:
    value: Q24781365
    source count: 1
    confidence: 0.2
    value label: Transient receptor potential cation channel subfamily V member 1
  P361:
    value: Q41797869
    source count: 1
    confidence: 0.2
    value label: Ankyrin repeat-containing domain superfamily
  P361:
    value: Q83138248
    source count: 1
    confidence: 0.2
    value label: Ion transport domain, protein family
  P361:
    value: Q83146468
    source count: 1
    confidence: 0.2
    value label: Ankyrin repeat-containing domain, protein family
  P361:
    value: Q95353759
    source count: 1
    confidence: 0.2
    value label: Ankyrin repeat, protein family
  P527:
    value: Q24778891
    source count: 1
    confidence: 0.2
    value label: ankyrin repeat-containing domain
  P527:
    value: Q24767982
    source count: 1
    confidence: 0.2
    value label: Ion transport domain
  P527:
    value: Q24784174
    source count: 1
    confidence: 0.2
    value label: ankyrin repeat
  P637:
    value: NP_001001445
    source count: 1
    confidence: 0.2
  P680:
    value: Q14860365
    source count: 1
    confidence: 0.2
    value label: nucleotide binding
  P680:
    value: Q14907992
    source count: 2
    confidence: 0.4
    value label: cation transmembrane transporter activity
  P680:
    value: Q14864714
    source count: 2
    confidence: 0.4
    value label: ion channel activity
  P680:
    value: Q167149
    source count: 2
    confidence: 0.4
    value label: protein binding
  P680:
    value: Q21441804
    source count: 2
    confidence: 0.4
    value label: temperature-gated ion channel activity
  P681:
    value: Q14353100
    source count: 1
    confidence: 0.2
    value label: cell projection
  P681:
    value: Q14349455
    source count: 5
    confidence: 1.0
    value label: membrane
  P681:
    value: Q14908160
    source count: 1
    confidence: 0.2
    value label: dendritic spine membrane
  P681:
    value: Q189073
    source count: 1
    confidence: 0.2
    value label: cell junction
  P681:
    value: Q14645640
    source count: 1
    confidence: 0.2
    value label: neuron projection

value: Q14897693
source count: 1
confidence: 0.2
value label: cellular response to nerve growth factor stimulus

value: Q14908171
source count: 1
confidence: 0.2
value label: urinary bladder smooth muscle contraction

value: Q14908173
source count: 2
confidence: 0.4
value label: detection of chemical stimulus involved in sensory perception of pain

value: Q2792936
source count: 1
confidence: 0.2
value label: lipid metabolism

value: Q14875882
source count: 1
confidence: 0.2
value label: cellular response to tumor necrosis factor

value: Q14908165
source count: 1
confidence: 0.2
value label: Trpv1

value: Q83310
source count: 1
confidence: 0.2
value label: house mouse

value: ENSMUSP00000099585
source count: 1
confidence: 0.2

value: ENSMUSP00000006106
source count: 1
confidence: 0.2

value: ENSMUSP00000104110
source count: 1
confidence: 0.2

value: ENSMUSP00000116400
source count: 1
confidence: 0.2

source: GOA
stated in qid: Q28018111
retrieved: 2019-02-14

source: GOA
stated in qid: Q28018111
retrieved: 2018-04-24

source: 2-aminoethoxydiphenyl borate is a common activator of TRPV1, TRPV2, and TRPV3
stated in qid: Q28585727
retrieved: 2018-04-24

source: Tmem100 Is a Regulator of TRPA1-TRPV1 Complex and Contributes to Persistent Pain
stated in qid: Q28591994
retrieved: 2019-02-14

source: Pirt, a phosphoinositide-binding protein, functions as a regulatory subunit of TRPV1
stated in qid: Q28509103
retrieved: 2019-02-14

source: The calcium-activated chloride channel anoctamin 1 acts as a heat sensor in nociceptive neurons
stated in qid: Q28506470
retrieved: 2019-02-14

source: Hydroxy-alpha-sanshool activates TRPV1 and TRPA1 in sensory neurons
stated in qid: Q28588024
retrieved: 2018-04-24

source: Impaired nociception and pain sensation in mice lacking the capsaicin receptor
stated in qid: Q28511370
retrieved: 2018-04-24

source: Identification of a protein that interacts with the vanilloid receptor
stated in qid: Q28511206
retrieved: 2019-02-14

source: Thermosensitive TRP channel pore turret is part of the temperature activation pathway
stated in qid: Q33859583
retrieved: 2018-04-24

source: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
stated in qid: Q34211397
retrieved: 2019-02-14

source: Impaired nociception and pain sensation in mice lacking the capsaicin receptor
stated in qid: Q28511370
retrieved: 2019-02-14

source: Hydroxy-alpha-sanshool activates TRPV1 and TRPA1 in sensory neurons
stated in qid: Q28588024
retrieved: 2019-02-14

source: P2X3 knock-out mice reveal a major sensory role for urothelially released ATP
stated in qid: Q28590638
retrieved: 2019-02-14

source: Altered urinary bladder function in mice lacking the vanilloid receptor TRPV1
stated in qid: Q28510240
retrieved: 2019-02-14

source: A single N-terminal cysteine in TRPV1 determines activation by pungent compounds from onion and garlic
stated in qid: Q28591657
retrieved: 2019-02-14

source: Pronociceptive response elicited by TRPA1 receptor activation in mice
stated in qid: Q28507198
retrieved: 2019-02-14

source: The vanilloid receptor TRPV1 is activated and sensitized by local anesthetics in rodent sensory neurons
stated in qid: Q28512507
retrieved: 2019-02-14

source: TRPV4 is a regulator of adipose oxidative metabolism, inflammation, and energy homeostasis
stated in qid: Q28586703
retrieved: 2019-02-14

source: Attenuated fever response in mice lacking TRPV1
stated in qid: Q28594508
retrieved: 2019-02-14

source: Mice lacking the transient receptor vanilloid potential 1 channel display normal thirst responses and central Fos activation to hypernatremia
stated in qid: Q28505340
retrieved: 2019-02-14

source: Cyclin-dependent kinase 5 modulates nociceptive signaling through direct phosphorylation of transient receptor potential vanilloid 1
stated in qid: Q24675401
retrieved: 2019-02-14

source: InterPro Release 71.0
stated in qid: Q58943792

source: UniProt
stated in qid: Q905695
retrieved: 2022-05-25

source: IUPHAR/BPS Guide to PHARMACOLOGY
stated in qid: Q17091219
retrieved: 2016-08-17

source: Q20641742
stated in qid: Q20641742
retrieved: 2022-03-20

source: ensembl Release 106
stated in qid: Q111699881

wikidata id: Q14908176
domain: protein
level: standard
html url: https://4ort.xyz/entity/transient-receptor-potential-cation-channel-subfamily-v-member-1-q14908176
markdown url: https://4ort.xyz/entity/transient-receptor-potential-cation-channel-subfamily-v-member-1-q14908176.md
facts url summary: https://4ort.xyz/entity/transient-receptor-potential-cation-channel-subfamily-v-member-1-q14908176/facts.json
facts url standard: https://4ort.xyz/entity/transient-receptor-potential-cation-channel-subfamily-v-member-1-q14908176/facts.json
facts url full: https://4ort.xyz/entity/transient-receptor-potential-cation-channel-subfamily-v-member-1-q14908176/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-09T07:14:21.258277Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T14:55:29.711424+00:00Z