# Transient receptor potential cation channel, subfamily M, member 8

> mammalian protein found in Mus musculus

**Wikidata**: [Q15324415](https://www.wikidata.org/wiki/Q15324415)  
**Source**: https://4ort.xyz/entity/transient-receptor-potential-cation-channel-subfamily-m-member-8


## References

1. UniProt
2. IUPHAR/BPS Guide to PHARMACOLOGY
3. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q8R4D5)
4. Q20641742
5. [The cold and menthol receptor TRPM8 contains a functionally important double cysteine motif](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8R4D5&geneProductId=UniProtKB:Q8R4D5)
6. [The menthol receptor TRPM8 is the principal detector of environmental cold](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8R4D5&geneProductId=UniProtKB:Q8R4D5)
7. [ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8R4D5&geneProductId=UniProtKB:Q8R4D5)
8. [A TRP channel that senses cold stimuli and menthol](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8R4D5&geneProductId=UniProtKB:Q8R4D5)
9. [Pirt, a phosphoinositide-binding protein, functions as a regulatory subunit of TRPV1](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8R4D5&geneProductId=UniProtKB:Q8R4D5)
10. [TRP channel-associated factors are a novel protein family that regulates TRPM8 trafficking and activity](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8R4D5&geneProductId=UniProtKB:Q8R4D5)
11. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8R4D5&geneProductId=UniProtKB:Q8R4D5)
12. [2-aminoethoxydiphenyl borate is a common activator of TRPV1, TRPV2, and TRPV3](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8R4D5&geneProductId=UniProtKB:Q8R4D5)
13. [TRPM8 is required for cold sensation in mice](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8R4D5&geneProductId=UniProtKB:Q8R4D5)
14. [Attenuated cold sensitivity in TRPM8 null mice](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8R4D5&geneProductId=UniProtKB:Q8R4D5)
15. ensembl Release 106
16. [Identifiers.org](https://registry.identifiers.org/registry/uniprot)