Transient receptor potential cation channel subfamily M member 8
type: Thing
description: mammalian protein found in Homo sapiens
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P129
  value: L-menthol
additional property: PropertyValue
  property ID: P129
  value: 5-benzyloxytryptamine
additional property: PropertyValue
  property ID: P129
  value: anandamide
additional property: PropertyValue
  property ID: P361
  value: Transient receptor potential cation channel subfamily M member 8
additional property: PropertyValue
  property ID: P361
  value: transient receptor potential channel
additional property: PropertyValue
  property ID: P361
  value: Ion transport domain, protein family
additional property: PropertyValue
  property ID: P527
  value: Ion transport domain
additional property: PropertyValue
  property ID: P637
  value: NP_076985
additional property: PropertyValue
  property ID: P637
  value: XP_011510112
additional property: PropertyValue
  property ID: P637
  value: XP_016860380
additional property: PropertyValue
  property ID: P680
  value: protein homodimerization activity
additional property: PropertyValue
  property ID: P680
  value: ion channel activity
additional property: PropertyValue
  property ID: P680
  value: protein binding
additional property: PropertyValue
  property ID: P681
  value: integral component of membrane
additional property: PropertyValue
  property ID: P681
  value: endoplasmic reticulum membrane
additional property: PropertyValue
  property ID: P681
  value: membrane
additional property: PropertyValue
  property ID: P682
  value: response to stimulus
additional property: PropertyValue
  property ID: P682
  value: sensory perception of temperature stimulus
additional property: PropertyValue
  property ID: P682
  value: cellular calcium ion homeostasis
additional property: PropertyValue
  property ID: P702
  value: TRPM8
additional property: PropertyValue
  property ID: P703
  value: Homo sapiens
additional property: PropertyValue
  property ID: P705
  value: ENSP00000386771
additional property: PropertyValue
  property ID: P705
  value: ENSP00000323926
additional property: PropertyValue
  property ID: P705
  value: ENSP00000347956
additional property: PropertyValue
  property ID: P7260
  value: 1.A.4.5.7
confidence:
  popularity graph score:
    score: 0.001
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 9
      unique citations norm: 0.004
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 9
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P129:
    value: Q407418
    source count: 1
    confidence: 0.2
    value label: L-menthol
  P129:
    value: Q4639574
    source count: 1
    confidence: 0.2
    value label: 5-benzyloxytryptamine
  P129:
    value: Q410228
    source count: 1
    confidence: 0.2
    value label: anandamide
  P129:
    value: Q422917
    source count: 1
    confidence: 0.2
    value label: cannabidiol
  P129:
    value: Q413546
    source count: 1
    confidence: 0.2
    value label: clotrimazole
  P352:
    value: Q7Z2W7
    source count: 1
    confidence: 0.2
  P361:
    value: Q24785144
    source count: 1
    confidence: 0.2
    value label: Transient receptor potential cation channel subfamily M member 8
  P361:
    value: Q304043
    source count: 1
    confidence: 0.2
    value label: transient receptor potential channel
  P361:
    value: Q83138248
    source count: 1
    confidence: 0.2
    value label: Ion transport domain, protein family
  P527:
    value: Q24767982
    source count: 1
    confidence: 0.2
    value label: Ion transport domain
  P637:
    value: NP_076985
    source count: 1
    confidence: 0.2
  P637:
    value: XP_011510112
    source count: 1
    confidence: 0.2
  P637:
    value: XP_016860380
    source count: 1
    confidence: 0.2
  P637:
    value: XP_024308900
    source count: 1
    confidence: 0.2
  P637:
    value: XP_024308901
    source count: 1
    confidence: 0.2
  P680:
    value: Q14762996
    source count: 1
    confidence: 0.2
    value label: protein homodimerization activity
  P680:
    value: Q14864714
    source count: 2
    confidence: 0.4
    value label: ion channel activity
  P680:
    value: Q167149
    source count: 1
    confidence: 0.2
    value label: protein binding
  P680:
    value: Q14891583
    source count: 2
    confidence: 0.4
    value label: calcium channel activity
  P681:
    value: Q14327652
    source count: 2
    confidence: 0.4
    value label: integral component of membrane
  P681:
    value: Q14329032
    source count: 1
    confidence: 0.2
    value label: endoplasmic reticulum membrane

value: Q14349455
source count: 3
confidence: 0.6
value label: membrane

value: Q79927
source count: 1
confidence: 0.2
value label: endoplasmic reticulum

value: Q424178
source count: 1
confidence: 0.2
value label: membrane raft

value: Q14859560
source count: 1
confidence: 0.2
value label: response to stimulus

value: Q21112879
source count: 1
confidence: 0.2
value label: sensory perception of temperature stimulus

value: Q14633887
source count: 1
confidence: 0.2
value label: cellular calcium ion homeostasis

value: Q14884611
source count: 1
confidence: 0.2
value label: cation transport

value: Q14859673
source count: 2
confidence: 0.4
value label: ion transport

value: Q15324395
source count: 1
confidence: 0.2
value label: TRPM8

value: Q15978631
source count: 1
confidence: 0.2
value label: Homo sapiens

value: ENSP00000386771
source count: 1
confidence: 0.2

value: ENSP00000323926
source count: 1
confidence: 0.2

value: ENSP00000347956
source count: 1
confidence: 0.2

value: ENSP00000390609
source count: 1
confidence: 0.2

value: ENSP00000396745
source count: 1
confidence: 0.2

value: 1.A.4.5.7
source count: 2
confidence: 0.4

source: Open Targets Platform
stated in qid: Q113138000
retrieved: 2023-08-14

source: GOA
stated in qid: Q28018111
retrieved: 2018-01-01

source: TRP channel-associated factors are a novel protein family that regulates TRPM8 trafficking and activity
stated in qid: Q24312097
retrieved: 2018-01-01

source: InterPro Release 71.0
stated in qid: Q58943792

source: UniProt
stated in qid: Q905695
retrieved: 2019-11-13

source: IUPHAR/BPS Guide to PHARMACOLOGY
stated in qid: Q17091219
retrieved: 2016-08-17

source: Q20641742
stated in qid: Q20641742
retrieved: 2020-05-30

source: Transporter Classification database
stated in qid: Q142667
retrieved: 2020-03-13

source: Ensembl Release 99
stated in qid: Q83867711

wikidata id: Q7671495
domain: protein
level: standard
html url: https://4ort.xyz/entity/transient-receptor-potential-cation-channel-subfamily-m-member-8-q7671495
markdown url: https://4ort.xyz/entity/transient-receptor-potential-cation-channel-subfamily-m-member-8-q7671495.md
facts url summary: https://4ort.xyz/entity/transient-receptor-potential-cation-channel-subfamily-m-member-8-q7671495/facts.json
facts url standard: https://4ort.xyz/entity/transient-receptor-potential-cation-channel-subfamily-m-member-8-q7671495/facts.json
facts url full: https://4ort.xyz/entity/transient-receptor-potential-cation-channel-subfamily-m-member-8-q7671495/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-08T22:32:26.571153Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T13:56:48.287846+00:00Z