Transient receptor potential cation channel subfamily M member 4
type: Thing
description: mammalian protein found in Homo sapiens
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P129
  value: adenosine triphosphate
additional property: PropertyValue
  property ID: P129
  value: spermine
additional property: PropertyValue
  property ID: P129
  value: adenosine
additional property: PropertyValue
  property ID: P361
  value: Transient receptor potential cation channel subfamily M member 4
additional property: PropertyValue
  property ID: P361
  value: transient receptor potential channel
additional property: PropertyValue
  property ID: P361
  value: Ion transport domain, protein family
additional property: PropertyValue
  property ID: P527
  value: Ion transport domain
additional property: PropertyValue
  property ID: P637
  value: NP_001182156
additional property: PropertyValue
  property ID: P637
  value: NP_001308210
additional property: PropertyValue
  property ID: P637
  value: NP_001308211
additional property: PropertyValue
  property ID: P680
  value: nucleotide binding
additional property: PropertyValue
  property ID: P680
  value: calcium channel activity
additional property: PropertyValue
  property ID: P680
  value: calmodulin binding
additional property: PropertyValue
  property ID: P681
  value: integral component of membrane
additional property: PropertyValue
  property ID: P681
  value: Golgi apparatus
additional property: PropertyValue
  property ID: P681
  value: membrane
additional property: PropertyValue
  property ID: P682
  value: adaptive immune response
additional property: PropertyValue
  property ID: P682
  value: vasoconstriction
additional property: PropertyValue
  property ID: P682
  value: immune system process
additional property: PropertyValue
  property ID: P702
  value: TRPM4
additional property: PropertyValue
  property ID: P703
  value: Homo sapiens
additional property: PropertyValue
  property ID: P705
  value: ENSP00000252826
additional property: PropertyValue
  property ID: P705
  value: ENSP00000407492
additional property: PropertyValue
  property ID: P705
  value: ENSP00000468989
additional property: PropertyValue
  property ID: P7260
  value: 1.A.4.5.4
confidence:
  popularity graph score:
    score: 0.002
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 15
      unique citations norm: 0.006
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 15
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P129:
    value: Q80863
    source count: 1
    confidence: 0.2
    value label: adenosine triphosphate
  P129:
    value: Q424597
    source count: 1
    confidence: 0.2
    value label: spermine
  P129:
    value: Q190012
    source count: 1
    confidence: 0.2
    value label: adenosine
  P129:
    value: Q318369
    source count: 1
    confidence: 0.2
    value label: adenosine monophosphate
  P129:
    value: Q185253
    source count: 1
    confidence: 0.2
    value label: adenosine diphosphate
  P352:
    value: Q8TD43
    source count: 1
    confidence: 0.2
  P361:
    value: Q24740597
    source count: 1
    confidence: 0.2
    value label: Transient receptor potential cation channel subfamily M member 4
  P361:
    value: Q304043
    source count: 1
    confidence: 0.2
    value label: transient receptor potential channel
  P361:
    value: Q83138248
    source count: 1
    confidence: 0.2
    value label: Ion transport domain, protein family
  P527:
    value: Q24767982
    source count: 1
    confidence: 0.2
    value label: Ion transport domain
  P637:
    value: NP_001182156
    source count: 1
    confidence: 0.2
  P637:
    value: NP_001308210
    source count: 1
    confidence: 0.2
  P637:
    value: NP_001308211
    source count: 1
    confidence: 0.2
  P637:
    value: NP_001308212
    source count: 1
    confidence: 0.2
  P637:
    value: NP_001308214
    source count: 1
    confidence: 0.2
  P680:
    value: Q14860365
    source count: 1
    confidence: 0.2
    value label: nucleotide binding
  P680:
    value: Q14891583
    source count: 1
    confidence: 0.2
    value label: calcium channel activity
  P680:
    value: Q14819275
    source count: 1
    confidence: 0.2
    value label: calmodulin binding
  P680:
    value: Q14864714
    source count: 1
    confidence: 0.2
    value label: ion channel activity
  P680:
    value: Q14817981
    source count: 2
    confidence: 0.4
    value label: ATP binding
  P681:
    value: Q14327652
    source count: 2
    confidence: 0.4
    value label: integral component of membrane

value: Q83181
source count: 2
confidence: 0.4
value label: Golgi apparatus

value: Q14349455
source count: 2
confidence: 0.4
value label: membrane

value: Q29548
source count: 5
confidence: 1.0
value label: plasma membrane

value: Q14817956
source count: 1
confidence: 0.2
value label: nucleoplasm

value: Q14887714
source count: 1
confidence: 0.2
value label: adaptive immune response

value: Q1067506
source count: 1
confidence: 0.2
value label: vasoconstriction

value: Q14916317
source count: 1
confidence: 0.2
value label: immune system process

value: Q14860483
source count: 1
confidence: 0.2
value label: positive regulation of canonical Wnt signaling pathway

value: Q14865156
source count: 1
confidence: 0.2
value label: regulation of membrane potential

value: Q15323765
source count: 1
confidence: 0.2
value label: TRPM4

value: Q15978631
source count: 1
confidence: 0.2
value label: Homo sapiens

value: ENSP00000252826
source count: 1
confidence: 0.2

value: ENSP00000407492
source count: 1
confidence: 0.2

value: ENSP00000468989
source count: 1
confidence: 0.2

value: ENSP00000469893
source count: 1
confidence: 0.2

value: ENSP00000470229
source count: 1
confidence: 0.2

value: 1.A.4.5.4
source count: 2
confidence: 0.4

source: GOA
stated in qid: Q28018111
retrieved: 2019-04-08

source: GOA
stated in qid: Q28018111
retrieved: 2018-11-07

source: Electron cryo-microscopy structure of a human TRPM4 channel
stated in qid: Q46656402
retrieved: 2019-04-08

source: Variants of Transient Receptor Potential Melastatin Member 4 in Childhood Atrioventricular Block
stated in qid: Q28118320
retrieved: 2019-04-08

source: Structure of the human TRPM4 ion channel in a lipid nanodisc
stated in qid: Q46053635
retrieved: 2019-04-08

source: Cloning and characterization of rat transient receptor potential-melastatin 4 (TRPM4)
stated in qid: Q24323009
retrieved: 2019-04-08

source: TRPM4 enhances cell proliferation through up-regulation of the β-catenin signaling pathway
stated in qid: Q24338716
retrieved: 2019-04-08

source: Impaired endocytosis of the ion channel TRPM4 is associated with human progressive familial heart block type I
stated in qid: Q24312557
retrieved: 2019-04-08

source: Trpm4 differentially regulates Th1 and Th2 function by altering calcium signaling and NFAT localization
stated in qid: Q24293007
retrieved: 2019-04-08

source: InterPro Release 71.0
stated in qid: Q58943792

source: UniProt
stated in qid: Q905695
retrieved: 2019-11-13

source: IUPHAR/BPS Guide to PHARMACOLOGY
stated in qid: Q17091219
retrieved: 2016-08-17

source: Q20641742
stated in qid: Q20641742
retrieved: 2020-05-30

source: Transporter Classification database
stated in qid: Q142667
retrieved: 2020-03-13

source: Ensembl Release 99
stated in qid: Q83867711

wikidata id: Q7671480
domain: protein
level: standard
html url: https://4ort.xyz/entity/transient-receptor-potential-cation-channel-subfamily-m-member-4-q7671480
markdown url: https://4ort.xyz/entity/transient-receptor-potential-cation-channel-subfamily-m-member-4-q7671480.md
facts url summary: https://4ort.xyz/entity/transient-receptor-potential-cation-channel-subfamily-m-member-4-q7671480/facts.json
facts url standard: https://4ort.xyz/entity/transient-receptor-potential-cation-channel-subfamily-m-member-4-q7671480/facts.json
facts url full: https://4ort.xyz/entity/transient-receptor-potential-cation-channel-subfamily-m-member-4-q7671480/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-07T19:43:05.034938Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T14:22:11.031041+00:00Z