# Transient receptor potential cation channel subfamily M member 2

> mammalian protein found in Homo sapiens

**Wikidata**: [Q7671477](https://www.wikidata.org/wiki/Q7671477)  
**Source**: https://4ort.xyz/entity/transient-receptor-potential-cation-channel-subfamily-m-member-2-q7671477


## References

1. UniProt
2. IUPHAR/BPS Guide to PHARMACOLOGY
3. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/O94759)
4. Q20641742
5. [Molecular cloning of a novel putative Ca2+ channel protein (TRPC7) highly expressed in brain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94759)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94759)
7. [Reciprocal regulation of actin cytoskeleton remodelling and cell migration by Ca2+ and Zn2+: role of TRPM2 channels](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94759)
8. [Four Ca2+ ions activate TRPM2 channels by binding in deep crevices near the pore but intracellularly of the gate](http://www.ebi.ac.uk/QuickGO/annotations?protein=O94759&geneProductId=UniProtKB:O94759)
9. [The proposed channel-enzyme transient receptor potential melastatin 2 does not possess ADP ribose hydrolase activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94759)
10. [ADP-Ribose Activates the TRPM2 Channel from the Sea Anemone Nematostella vectensis Independently of the NUDT9H Domain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94759)
11. [Four Ca2+ ions activate TRPM2 channels by binding in deep crevices near the pore but intracellularly of the gate](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94759)
12. [Modulation of activation and inactivation by Ca2+ and 2-APB in the pore of an archetypal TRPM channel from Nematostella vectensis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94759)
13. [Structures and gating mechanism of human TRPM2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94759)
14. [Structure of a TRPM2 channel in complex with Ca2+ explains unique gating regulation.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94759)
15. [Functional Characterisation of a TRPM2 orthologue from the sea anemone Nematostella vectensis in human cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94759)
16. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=O94759&geneProductId=UniProtKB:O94759)
17. [Molecular cloning of a novel putative Ca2+ channel protein (TRPC7) highly expressed in brain](http://www.ebi.ac.uk/QuickGO/annotations?protein=O94759&geneProductId=UniProtKB:O94759)
18. Ensembl Release 99
19. Transporter Classification database