# Transforming growth factor, beta receptor II

> mammalian protein found in Mus musculus

**Wikidata**: [Q14911588](https://www.wikidata.org/wiki/Q14911588)  
**Source**: https://4ort.xyz/entity/transforming-growth-factor-beta-receptor-ii


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q62312)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62312&geneProductId=UniProtKB:Q62312)
5. [Cholesterol suppresses cellular TGF-beta responsiveness: implications in atherogenesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62312&geneProductId=UniProtKB:Q62312)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62312)
7. [RLP, a novel Ras-like protein, is an immediate-early transforming growth factor-beta (TGF-beta) target gene that negatively regulates transcriptional activity induced by TGF-beta](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62312)
8. [LRG1 promotes angiogenesis by modulating endothelial TGF-β signalling.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62312)
9. [Stem cell antigen-1 enhances tumorigenicity by disruption of growth differentiation factor-10 (GDF10)–dependent TGF-β signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62312)
10. [TGF-beta activates Erk MAP kinase signalling through direct phosphorylation of ShcA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62312)
11. [TGF-beta signaling specifies axons during brain development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62312)
12. [Dlg5 interacts with the TGF-β receptor and promotes its degradation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62312)
13. [VE-cadherin is a critical endothelial regulator of TGF-beta signalling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62312)
14. [Heart and liver defects and reduced transforming growth factor beta2 sensitivity in transforming growth factor beta type III receptor-deficient embryos](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62312)
15. [Heart and liver defects and reduced transforming growth factor beta2 sensitivity in transforming growth factor beta type III receptor-deficient embryos](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62312&geneProductId=UniProtKB:Q62312)
16. [Cholesterol suppresses cellular TGF-beta responsiveness: implications in atherogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62312)
17. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62312)
18. [Cellular mechanisms of fatal early-onset autoimmunity in mice with the T cell-specific targeting of transforming growth factor-beta receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62312)
19. [TGF-β signaling plays an essential role in the growth and maintenance of intervertebral disc tissue](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62312)
20. [Requirement for TGFbeta receptor signaling during terminal lens fiber differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62312)
21. [Conditional inactivation of Tgfbr2 in cranial neural crest causes cleft palate and calvaria defects](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62312)
22. [Activation of the murine type II transforming growth factor-beta receptor gene: up-regulation and function of the transcription factor Elf-3/Ert/Esx/Ese-1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62312)
23. [TGF-β signaling plays an essential role in the growth and maintenance of intervertebral disc tissue](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62312&geneProductId=UniProtKB:Q62312)
24. [Mesodermal deletion of transforming growth factor-beta receptor II disrupts lung epithelial morphogenesis: cross-talk between TGF-beta and Sonic hedgehog pathways](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62312)
25. [Ectopic expression of the transforming growth factor beta type II receptor disrupts mesoderm organisation during mouse gastrulation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62312)
26. [Defective ALK5 signaling in the neural crest leads to increased postmigratory neural crest cell apoptosis and severe outflow tract defects](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62312&geneProductId=UniProtKB:Q62312)
27. [Cardiovascular malformations with normal smooth muscle differentiation in neural crest-specific type II TGFbeta receptor (Tgfbr2) mutant mice](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62312&geneProductId=UniProtKB:Q62312)
28. [The role of transforming growth factor-beta signalling in the patterning of the proximal processes of the murine dentary](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62312)
29. [Defective ALK5 signaling in the neural crest leads to increased postmigratory neural crest cell apoptosis and severe outflow tract defects](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62312)
30. [Hepatic Notch2 deficiency leads to bile duct agenesis perinatally and secondary bile duct formation after weaning](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62312)
31. [Effect of conditional knockout of the type II TGF-beta receptor gene in mammary epithelia on mammary gland development and polyomavirus middle T antigen induced tumor formation and metastasis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62312)
32. [Autocrine/paracrine TGFbeta1 is required for the development of epidermal Langerhans cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62312)
33. [Epithelial and ectomesenchymal role of the type I TGF-beta receptor ALK5 during facial morphogenesis and palatal fusion](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62312)
34. [The TGFβ type II receptor plays a critical role in the endothelial cells during cardiac development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62312)
35. [Tgfbeta signaling is required for atrioventricular cushion mesenchyme remodeling during in vivo cardiac development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62312)
36. [TGFβ Triggers miR-143/145 Transfer From Smooth Muscle Cells to Endothelial Cells, Thereby Modulating Vessel Stabilization](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62312)
37. [Cardiovascular malformations with normal smooth muscle differentiation in neural crest-specific type II TGFbeta receptor (Tgfbr2) mutant mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62312)