# Transforming growth factor beta receptor 2

> mammalian protein found in Homo sapiens

**Wikidata**: [Q7670161](https://www.wikidata.org/wiki/Q7670161)  
**Source**: https://4ort.xyz/entity/transforming-growth-factor-beta-receptor-2-q7670161


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P37173)
3. Q20641742
4. [TGF beta signals through a heteromeric protein kinase receptor complex](http://www.ebi.ac.uk/QuickGO/annotations?protein=P37173&geneProductId=UniProtKB:P37173)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P37173&geneProductId=UniProtKB:P37173)
6. [The soluble exoplasmic domain of the type II transforming growth factor (TGF)-beta receptor. A heterogeneously glycosylated protein with high affinity and selectivity for TGF-beta ligands](http://www.ebi.ac.uk/QuickGO/annotations?protein=P37173&geneProductId=UniProtKB:P37173)
7. [Activation of a TGF-beta-specific multistep gene expression program in mature macrophages requires glucocorticoid-mediated surface expression of TGF-beta receptor II](http://www.ebi.ac.uk/QuickGO/annotations?protein=P37173&geneProductId=UniProtKB:P37173)
8. [Endoglin is a component of the transforming growth factor-beta receptor system in human endothelial cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P37173&geneProductId=UniProtKB:P37173)
9. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37173)
10. [Type III TGF-beta receptor-independent signalling of TGF-beta2 via TbetaRII-B, an alternatively spliced TGF-beta type II receptor](http://www.ebi.ac.uk/QuickGO/annotations?protein=P37173&geneProductId=UniProtKB:P37173)
11. [Identification of human activin and TGF beta type I receptors that form heteromeric kinase complexes with type II receptors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37173)
12. [SARA, a FYVE domain protein that recruits Smad2 to the TGFbeta receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37173)
13. [Transforming growth factor-beta receptor-associated protein 1 is a Smad4 chaperone](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37173)
14. [Interaction of transforming growth factor beta receptors with apolipoprotein J/clusterin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37173)
15. [SCUBE3 is an endogenous TGF-β receptor ligand and regulates the epithelial-mesenchymal transition in lung cancer](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37173)
16. [TGF-β signalling is mediated by two autonomously functioning TβRI:TβRII pairs](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37173)
17. [Critical role of endoglin in tumor cell plasticity of Ewing sarcoma and melanoma](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37173)
18. [TGF-beta-induced apoptosis is mediated by the adapter protein Daxx that facilitates JNK activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37173)
19. [Emilin1 links TGF-beta maturation to blood pressure homeostasis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37173)
20. [MED12 controls the response to multiple cancer drugs through regulation of TGF-β receptor signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37173)
21. [Crystal structure of the human TbetaR2 ectodomain--TGF-beta3 complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37173)
22. [DIP2 disco-interacting protein 2 homolog A (Drosophila) is a candidate receptor for follistatin-related protein/follistatin-like 1--analysis of their binding with TGF-β superfamily proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37173)
23. [WFIKKN1 and WFIKKN2 bind growth factors TGFβ1, BMP2 and BMP4 but do not inhibit their signalling activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37173)
24. [Interaction and functional interplay between endoglin and ALK-1, two components of the endothelial transforming growth factor-beta receptor complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37173)
25. [Activation of signalling by the activin receptor complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37173)
26. [Sorting nexin 6, a novel SNX, interacts with the transforming growth factor-beta family of receptor serine-threonine kinases](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37173)
27. [Extracellular and cytoplasmic domains of endoglin interact with the transforming growth factor-beta receptors I and II](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37173)
28. [Cooperative assembly of TGF-beta superfamily signaling complexes is mediated by two disparate mechanisms and distinct modes of receptor binding](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37173)
29. [The soluble exoplasmic domain of the type II transforming growth factor (TGF)-beta receptor. A heterogeneously glycosylated protein with high affinity and selectivity for TGF-beta ligands](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37173)
30. [HCV NS3 protease enhances liver fibrosis via binding to and activating TGF-β type I receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37173)
31. [Endoglin is a component of the transforming growth factor-beta receptor system in human endothelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37173)
32. [TGF beta signals through a heteromeric protein kinase receptor complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37173)
33. [Activation of a TGF-beta-specific multistep gene expression program in mature macrophages requires glucocorticoid-mediated surface expression of TGF-beta receptor II](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37173)
34. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37173)
35. [Type III TGF-beta receptor-independent signalling of TGF-beta2 via TbetaRII-B, an alternatively spliced TGF-beta type II receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37173)
36. [Cholesterol suppresses cellular TGF-beta responsiveness: implications in atherogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37173)
37. [Syntenin regulates TGF-β1-induced Smad activation and the epithelial-to-mesenchymal transition by inhibiting caveolin-mediated TGF-β type I receptor internalization](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37173)
38. [Receptor-associated Mad homologues synergize as effectors of the TGF-beta response](http://www.ebi.ac.uk/QuickGO/annotations?protein=P37173&geneProductId=UniProtKB:P37173)
39. [Receptor-associated Mad homologues synergize as effectors of the TGF-beta response](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37173)
40. [Feedback between p21 and reactive oxygen production is necessary for cell senescence](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37173)
41. [Requirement of type III TGF-beta receptor for endocardial cell transformation in the heart](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37173)
42. [GASDERMIN, suppressed frequently in gastric cancer, is a target of LMO1 in TGF-beta-dependent apoptotic signalling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37173)
43. [MicroRNA-590 is an EMT-suppressive microRNA involved in the TGFβ signaling pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37173)
44. [Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37173)
45. [Twisted gastrulation (Tsg) is regulated by Tob and enhances TGF-beta signaling in activated T lymphocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37173)
46. Ensembl Release 99