# transforming growth factor beta 2

> mammalian protein found in Homo sapiens

**Wikidata**: [Q7670154](https://www.wikidata.org/wiki/Q7670154)  
**Source**: https://4ort.xyz/entity/transforming-growth-factor-beta-2-q7670154


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P61812)
3. Q20641742
4. [Type III TGF-beta receptor-independent signalling of TGF-beta2 via TbetaRII-B, an alternatively spliced TGF-beta type II receptor](http://www.ebi.ac.uk/QuickGO/annotations?protein=P61812&geneProductId=UniProtKB:P61812)
5. [TGF beta signals through a heteromeric protein kinase receptor complex](http://www.ebi.ac.uk/QuickGO/annotations?protein=P61812&geneProductId=UniProtKB:P61812)
6. [The soluble exoplasmic domain of the type II transforming growth factor (TGF)-beta receptor. A heterogeneously glycosylated protein with high affinity and selectivity for TGF-beta ligands](http://www.ebi.ac.uk/QuickGO/annotations?protein=P61812&geneProductId=UniProtKB:P61812)
7. [Cloning and developmental expression of the chick type II and type III TGF beta receptors](http://www.ebi.ac.uk/QuickGO/annotations?protein=P61812&geneProductId=UniProtKB:P61812)
8. [Transforming growth factor beta2 is a neuronal death-inducing ligand for amyloid-beta precursor protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61812)
9. [Type III TGF-beta receptor-independent signalling of TGF-beta2 via TbetaRII-B, an alternatively spliced TGF-beta type II receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61812)
10. [The soluble exoplasmic domain of the type II transforming growth factor (TGF)-beta receptor. A heterogeneously glycosylated protein with high affinity and selectivity for TGF-beta ligands](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61812)
11. [Cloning and developmental expression of the chick type II and type III TGF beta receptors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61812)
12. [Transforming growth factor-beta (TGF-beta)](http://www.ebi.ac.uk/QuickGO/annotations?protein=P61812&geneProductId=UniProtKB:P61812)
13. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P61812&geneProductId=UniProtKB:P61812)
14. [Transforming growth factor beta2 is a neuronal death-inducing ligand for amyloid-beta precursor protein](http://www.ebi.ac.uk/QuickGO/annotations?protein=P61812&geneProductId=UniProtKB:P61812)
15. [Requirement of type III TGF-beta receptor for endocardial cell transformation in the heart](http://www.ebi.ac.uk/QuickGO/annotations?protein=P61812&geneProductId=UniProtKB:P61812)
16. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61812)
17. [Transforming growth factor-beta bound to soluble derivatives of the beta amyloid precursor protein of Alzheimer's disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61812)
18. [A role of the latent TGF-beta 1-binding protein in the assembly and secretion of TGF-beta 1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61812)
19. [Specific sequence motif of 8-Cys repeats of TGF-beta binding proteins, LTBPs, creates a hydrophobic interaction surface for binding of small latent TGF-beta](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61812)
20. [Mechanisms for asporin function and regulation in articular cartilage](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61812)
21. [GARP (LRRC32) is essential for the surface expression of latent TGF-beta on platelets and activated FOXP3+ regulatory T cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61812)
22. [Association of the small latent transforming growth factor-beta with an eight cysteine repeat of its binding protein LTBP-1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61812)
23. [Using an in Situ Proximity Ligation Assay to Systematically Profile Endogenous Protein–Protein Interactions in a Pathway Network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61812)
24. [Transforming growth factor-beta (TGF-beta)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61812)
25. [TGF beta signals through a heteromeric protein kinase receptor complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61812)
26. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61812)
27. [Requirement of type III TGF-beta receptor for endocardial cell transformation in the heart](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61812)
28. [Disease-related quantitation of TGF-beta3 in human aqueous humor](http://www.ebi.ac.uk/QuickGO/annotations?protein=P61812&geneProductId=UniProtKB:P61812)
29. [HCV NS3 protease enhances liver fibrosis via binding to and activating TGF-β type I receptor](http://www.ebi.ac.uk/QuickGO/annotations?protein=P61812&geneProductId=UniProtKB:P61812)
30. [Disease-related quantitation of TGF-beta3 in human aqueous humor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61812)
31. [HCV NS3 protease enhances liver fibrosis via binding to and activating TGF-β type I receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61812)
32. [Retinal neurons regulate proliferation of postnatal progenitors and Müller glia in the rat retina via TGF beta signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61812)
33. [Cellular response to hypoxia involves signaling via Smad proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61812)
34. [Opposite regulation of transforming growth factors-beta2 and -beta3 expression in the human endometrium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61812)
35. [Transforming growth factor-beta2 enhances differentiation of cardiac myocytes from embryonic stem cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61812)
36. [Integrin beta1-mediated signaling is involved in transforming growth factor-beta2-promoted migration in human lens epithelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61812)
37. [Transforming growth factor beta2 regulates growth and differentiation of pulp cells via ALK5/Smad2/3](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61812)
38. [Targeted inhibition of p57 and p15 blocks transforming growth factor beta-inhibited proliferation of primary cultured human limbal epithelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61812)
39. [Reactive oxygen species mediates the apoptosis induced by transforming growth factor beta(2) in human lens epithelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61812)
40. [TGF-β2 suppresses macrophage cytokine production and mucosal inflammatory responses in the developing intestine](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61812)
41. [Involvement of PI3K/Akt pathway in TGF-beta2-mediated epithelial mesenchymal transition in human lens epithelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61812)
42. [Complementary DNA for human glioblastoma-derived T cell suppressor factor, a novel member of the transforming growth factor-beta gene family](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61812)
43. [Transforming growth factor beta2 regulates growth and differentiation of pulp cells via ALK5/Smad2/3](http://www.ebi.ac.uk/QuickGO/annotations?protein=P61812&geneProductId=UniProtKB:P61812)
44. [Transforming growth factor-beta2 and connective tissue growth factor in proliferative vitreoretinal diseases: possible involvement of hyalocytes and therapeutic potential of Rho kinase inhibitor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61812)
45. [Transforming growth factor-beta1, transforming growth factor-beta2, and transforming growth factor-beta3 enhance ovarian cancer metastatic potential by inducing a Smad3-dependent epithelial-to-mesenchymal transition](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61812)
46. [Epithelial-derived TGF-beta2 modulates basal and wound-healing subepithelial matrix homeostasis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61812)
47. [Tumor suppressor FLCN inhibits tumorigenesis of a FLCN-null renal cancer cell line and regulates expression of key molecules in TGF-beta signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61812)
48. [TGF-beta1 and TGF-beta2 expression after traumatic human spinal cord injury](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61812)
49. [Endothelial cell barrier impairment induced by glioblastomas and transforming growth factor beta2 involves matrix metalloproteinases and tight junction proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61812)
50. [Bone formation zones in heterotopic ossifications: histologic findings and increased expression of bone morphogenetic protein 2 and transforming growth factors beta2 and beta3](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61812)